Comparative Study of Perioperative Cardiac Injury in Patients With Functional Adrenal Tumors

NCT ID: NCT07182175

Last Updated: 2025-09-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ENROLLING_BY_INVITATION

Total Enrollment

150 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-09-19

Study Completion Date

2026-05-29

Brief Summary

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The main goal of this study is to follow patients with functional adrenal tumors during the time before and after their surgery.

The main questions it aims to answer are:

* What heart and blood pressure changes do patients with different types of adrenal tumors have before surgery?
* What factors affect how the heart and blood pressure recover after surgery?
* Do the heart and blood pressure conditions before surgery influence recovery and the risk of heart or brain problems after surgery?

Patients will have heart ultrasound checks and health monitoring before and after surgery. The results will help doctors choose the right medicines before surgery, better understand possible risks during the operation, and make safer treatment plans for patients with functional adrenal tumors.

Detailed Description

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Conditions

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Primary Aldosteronism Adrenal Tumor Cushing s Syndrome Pheochromocytoma/Paraganglioma (PPGL)

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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primary aldosteronism

No interventions assigned to this group

Cushing s Syndrome

No interventions assigned to this group

Pheochromocytoma/Paraganglioma (PPGL)

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Patients diagnosed in the Department of Urology, Peking University First Hospital with pheochromocytoma and paraganglioma (PPGL), primary aldosteronism (PA), or Cushing syndrome (CS);
* Written informed consent obtained.

Exclusion Criteria

* Patients with PPGL, PA, or CS who receive medication or conservative treatment and are not eligible for surgical resection;
* Patients with communication disorders or severe physical impairments such as aphasia, or visual/hearing disabilities;
* Patients with severe mental illness who cannot cooperate with the study;
* Pregnant women or patients otherwise deemed unsuitable for participation by the investigators.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Peking University First Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Peking University First Hospital

Beijing, , China

Site Status

Countries

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China

Other Identifiers

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2024yan411-002

Identifier Type: -

Identifier Source: org_study_id

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