Prospective Study on the Incidence of Adrenal Crisis in Patients With Chronic Adrenal Insufficiency

NCT ID: NCT01184209

Last Updated: 2014-01-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

444 participants

Study Classification

OBSERVATIONAL

Study Start Date

2007-02-28

Study Completion Date

2011-08-31

Brief Summary

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Prospective study to evaluate incidence, causes and potential risk factors for adrenal crisis in patients with chronic adrenal insufficiency.

Detailed Description

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This is a prospective study following patients with chronic adrenal insufficiency by contacting them every 6 months via questionnaires and telephone. QUestionnaires assess incidence and causes of adrenal crisis, frequency of hospitalization.

Conditions

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Adrenal Insufficiency

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* chronic primary or secondary adrenal insufficiency requiring glucocorticoid substitution therapy

Exclusion Criteria

* adrenocortical carcinoma
* long term glucocorticoid treatment above 7.5 mg prednisone equivalent dose for other reasons than adrenal insufficiency
* age \< 18 years
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Ludwig-Maximilians - University of Munich

OTHER

Sponsor Role collaborator

Charite University, Berlin, Germany

OTHER

Sponsor Role collaborator

University of Wuerzburg

OTHER

Sponsor Role lead

Responsible Party

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Bruno Allolio

MD

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Bruno Allolio, MD

Role: STUDY_CHAIR

University of Wuerzburg

Locations

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University of Berlin

Berlin, , Germany

Site Status

University of Wuerzburg

Würzburg, , Germany

Site Status

Countries

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Germany

References

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Hahner S, Spinnler C, Fassnacht M, Burger-Stritt S, Lang K, Milovanovic D, Beuschlein F, Willenberg HS, Quinkler M, Allolio B. High incidence of adrenal crisis in educated patients with chronic adrenal insufficiency: a prospective study. J Clin Endocrinol Metab. 2015 Feb;100(2):407-16. doi: 10.1210/jc.2014-3191. Epub 2014 Nov 24.

Reference Type DERIVED
PMID: 25419882 (View on PubMed)

Other Identifiers

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WueAC17/07

Identifier Type: -

Identifier Source: org_study_id

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