Mortality Predictors in Coronary Care in Turkey

NCT ID: NCT05296694

Last Updated: 2023-02-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

2560 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-09-01

Study Completion Date

2022-10-15

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This study was undertaken to investigate and document the mortality rates and predictors in coronary care unit (CCU) patients in Turkey.

It is designed to be a multicenter, observational, cross-sectional, and descriptive study. It will be conducted in 50 centers in 12 regions of Turkey. The study does not include any interventional or treatment procedures.

At the end of the study, clinicians will have up-to-date information about predictors of mortality in CCU patients.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

The MORCOR-TURK study will be conducted as a nationwide registry in 50 tertiary cardiology centers selected from each EuroStat NUTS region in Turkey according to their population sample weight, prioritizing the volume of hospitals in each region. All consecutive patients admitted to the coronary care units (CCU) will be prospectively admitted during a predefined period of 1 month. The study will be conducted by cardiologists in hospitals who regularly treat cardiac patients. Led by the Cardiology Department of Kutahya Evliya Celebi Research and Training Hospital, 50 centers will be included in the study.

There has not been any large-scale epidemiological study on coronary care patients in Turkey recently. Therefore, up-to-date information in this group of patients is lacking. In particular, significant reductions in mortality and morbidity are expected, thanks to improved medical and interventional facilities. In the light of current data, the investigators designed a large-scale study to document mortality rates and predictors in CCU patients.

In this study, the investigators will include consecutive patients admitted to CCU with cardiovascular indications in all participating centers. Patients will be followed and treated by experienced cardiologists and no further experimental intervention will be planned. In the first part of the study, the investigators will record in-hospital mortality rates and try to identify the best predictors. In the second part of the MORCOR-TURK trial which will have a cohort design, the investigators will follow the successfully discharged patients for 1 year. At the end of the follow-up, investigators will assess the risk factors and predictors of cardiovascular events as secondary endpoints.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Death, Cardiac

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Coronary Care Patients

All patients admitted to coronary care unit with cardiovascular diseases.

No interventions assigned to this group

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* 18 years of age or older
* hospitalized with cardiovascular diseases
* individuals (or relatives for unconscious patients) who gave written informed consent

Exclusion Criteria

* younger than 18 years of age
* rejecting to sign an informed consent
* hospitalized to CCU by other departments with noncardiac indications
* patients with active severe noncardiac chronic disease (chronic obstructive pulmonary disease, systemic diseases, and malignancy)
* no vital signs despite adequate cardiopulmonary resuscitation during hospitalization
* rejected to stay in CCU and discharged with his/her own request
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Afyonkarahisar Health Sciences University

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

İbrahim Ersoy, MD

Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Fatih Kahraman, MD

Role: STUDY_DIRECTOR

Kutahya Health Sciences University Evliya Celebi Research and Training Hospital

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Afyonkarahisar Health Sciences University

Afyonkarahisar, , Turkey (Türkiye)

Site Status

Kutahya Evliya Celebi Research and Training Hospital

Kütahya, , Turkey (Türkiye)

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Turkey (Türkiye)

References

Explore related publications, articles, or registry entries linked to this study.

Ratcliffe JA, Wilson E, Islam S, Platsman Z, Leou K, Williams G, Lucido D, Moustakakis E, Rachko M, Bergmann SR. Mortality in the coronary care unit. Coron Artery Dis. 2014 Jan;25(1):60-5. doi: 10.1097/MCA.0000000000000043.

Reference Type BACKGROUND
PMID: 24121428 (View on PubMed)

Filizcan U, Kurc E, Cetemen S, Soylu O, Aydogan H, Bayserke O, Yilmaz M, Uyarel H, Ergelen M, Orhan G, Ugurlucan M, Eren E, Yekeler I. Mortality predictors in ST-elevated myocardial infarction patients undergoing coronary artery bypass grafting. Angiology. 2011 Jan;62(1):68-73. doi: 10.1177/0003319710369103. Epub 2010 May 12.

Reference Type BACKGROUND
PMID: 20462895 (View on PubMed)

Hayiroglu MI, Keskin M, Uzun AO, Yildirim DI, Kaya A, Cinier G, Bozbeyoglu E, Yildirimturk O, Kozan O, Pehlivanoglu S. Predictors of In-Hospital Mortality in Patients With ST-Segment Elevation Myocardial Infarction Complicated With Cardiogenic Shock. Heart Lung Circ. 2019 Feb;28(2):237-244. doi: 10.1016/j.hlc.2017.10.023. Epub 2017 Nov 14.

Reference Type BACKGROUND
PMID: 29191504 (View on PubMed)

Campanile A, Castellani C, Santucci A, Annunziata R, Tutarini C, Reccia MR, Del Pinto M, Verdecchia P, Cavallini C. Predictors of in-hospital and long-term mortality in unselected patients admitted to a modern coronary care unit. J Cardiovasc Med (Hagerstown). 2019 May;20(5):327-334. doi: 10.2459/JCM.0000000000000785.

Reference Type BACKGROUND
PMID: 30865139 (View on PubMed)

Taylan G, Kaya C, Ozbek M, Kurt F, Kacmaz Y, Akkaya F, Kahraman F, Yilmaz AS. Short-Term Prognosis of Elderly Patients Admitted to the Coronary Care Unit: A Subgroup Analysis of the MORCOR-TURK (Mortality and Morbidity in Coronary Care Units in Turkiye) Trial. Turk Kardiyol Dern Ars. 2024 Sep;52(6):411-419. doi: 10.5543/tkda.2024.51282.

Reference Type DERIVED
PMID: 39225647 (View on PubMed)

Kahraman F, Ersoy I, Yilmaz AS, Atici A, Tekin AM, Acar B, Kaya C, Kara F, Kurt F, Avci Demir F, Cerik IB, Yilmaz I, Adali MK, Yeni M, Tascanov MB, Yenercag M, Sahin M, Duz R, Gulasti S, Omur SE, Topuz S, Hidayet S, Kacmaz Y, Aygul N. Rationale, Design, and Methodology of the MORCOR-TURK Trial: Predictors of In-hospital MORtality in CORonary Care Patients in Turkey. Anatol J Cardiol. 2023 May;27(5):258-265. doi: 10.14744/AnatolJCardiol.2022.2824.

Reference Type DERIVED
PMID: 37119186 (View on PubMed)

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

3450

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

CTO-PCI in Heart Failure Patients
NCT05632653 NOT_YET_RECRUITING NA