Distribution of Pulmonary Ventilation in Lateral Decubitus of Healthy Adults Under Non-Invasive Mechanical Ventilation
NCT ID: NCT06489509
Last Updated: 2024-07-09
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
10 participants
INTERVENTIONAL
2017-12-06
2018-07-08
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
CROSSOVER
SUPPORTIVE_CARE
DOUBLE
Study Groups
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Supine position
Supine experimental position
Positive End Expiratory Pressure 5 H2O
Positive End Expiratory Pressure 5 H2O from CPAP apparatus
Positive End Expiratory Pressure 10 H2O
Positive End Expiratory Pressure 5 H2O from CPAP apparatus
Right position
Right lateral decubitus
Positive End Expiratory Pressure 5 H2O
Positive End Expiratory Pressure 5 H2O from CPAP apparatus
Positive End Expiratory Pressure 10 H2O
Positive End Expiratory Pressure 5 H2O from CPAP apparatus
Left position
Left lateral decubitus
Positive End Expiratory Pressure 5 H2O
Positive End Expiratory Pressure 5 H2O from CPAP apparatus
Positive End Expiratory Pressure 10 H2O
Positive End Expiratory Pressure 5 H2O from CPAP apparatus
Interventions
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Positive End Expiratory Pressure 5 H2O
Positive End Expiratory Pressure 5 H2O from CPAP apparatus
Positive End Expiratory Pressure 10 H2O
Positive End Expiratory Pressure 5 H2O from CPAP apparatus
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* BMI\>40
* Smoking history
18 Years
35 Years
ALL
Yes
Sponsors
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Attikon Hospital
OTHER
Responsible Party
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Konstantinos Grigoriadis
Chief of allied health professions
Principal Investigators
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Konstantinos Grigoriadis, Dr
Role: PRINCIPAL_INVESTIGATOR
PT, Attikon University Hospital
Anna Grigoriadou, MSc
Role: STUDY_DIRECTOR
PT, Attikon University Hospital
Frantzeska Frantzeskaki
Role: STUDY_DIRECTOR
MD, Attikon University Hospital
Ioannis Efstathiou
Role: STUDY_DIRECTOR
PT, Attikon University Hospital
Iraklis Tsangaris
Role: STUDY_CHAIR
Professor, Attikon University Hospital
Locations
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Attikon University Hospital
Athens, Attica, Greece
Grigoriadis Konstantinos
Athens, Attica, Greece
Countries
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References
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Schnidrig S, Casaulta C, Schibler A, Riedel T. Influence of end-expiratory level and tidal volume on gravitational ventilation distribution during tidal breathing in healthy adults. Eur J Appl Physiol. 2013 Mar;113(3):591-8. doi: 10.1007/s00421-012-2469-7. Epub 2012 Aug 8.
Sharma JP, Salhotra R, Kumar S, Tyagi A, Sethi AK. Noninvasive lung recruitment maneuver prevents reintubation and reduces ICU stay. Lung India. 2016 Jan-Feb;33(1):99-101. doi: 10.4103/0970-2113.173070. No abstract available.
Hurewitz AN, Susskind H, Harold WH. Obesity alters regional ventilation in lateral decubitus position. J Appl Physiol (1985). 1985 Sep;59(3):774-83. doi: 10.1152/jappl.1985.59.3.774.
Lobo B, Hermosa C, Abella A, Gordo F. Electrical impedance tomography. Ann Transl Med. 2018 Jan;6(2):26. doi: 10.21037/atm.2017.12.06.
Miura MC, Ribeiro de Carvalho CR, Yamada da Silveira LT, de Moraes Regenga M, Petri Damiani L, Fu C. The effects of recruitment maneuver during noninvasive ventilation after coronary bypass grafting: A randomized trial. J Thorac Cardiovasc Surg. 2018 Dec;156(6):2170-2177.e1. doi: 10.1016/j.jtcvs.2018.05.004. Epub 2018 May 28.
Nishimura M. Electrical Impedance Tomography: The Promise of Noninvasive Lung Images at the Bedside. Respir Care. 2020 Mar;65(3):402-403. doi: 10.4187/respcare.07716. No abstract available.
Other Identifiers
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EBD2878
Identifier Type: -
Identifier Source: org_study_id
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