Pleural Effusion Drainage in Mechanically Ventilated Patients Monitored by EIT

NCT ID: NCT03231072

Last Updated: 2022-07-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

19 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-01-31

Study Completion Date

2022-03-30

Brief Summary

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Evacuation of pleural effusion (PE) represents a disputable therapy in mechanically ventilated patients. Patients on mechanical ventilation indicated by the physician to pleural fluid evacuation will be monitored throughout the procedure by electrical impedance tomography (EIT) and concurrently end-expiratory lung volume (EELV) will be measured in order to describe impact of PE evacuation on aeration and ventilation of the lungs.

Detailed Description

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Critically ill patients treated in intensive care units have a disorder of distribution and volume of body fluids due to principal illness and some therapeutic interventions. One of its manifestations is pleural effusion (PE) formation.

Patients on mechanical ventilation indicated by treating physician to pleural fluid evacuation will be monitored throughout the procedure by electrical impedance tomography (EIT) and concurrently end-expiratory lung volume (EELV) will be measured. The purpose of the study is to better understand impact of PE evacuation on aeration and ventilation of the lungs.

Conditions

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Pleural Effusion Drainage Electric Impedance Tomography

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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Electrical Impedance Tomography record

Electrical Impedance Tomography monitoring of the pleural effusion evacuation.

Group Type EXPERIMENTAL

Electrical Impedance Tomography record

Intervention Type DEVICE

Monitoring of pleural effusion evacuation by means of EIT

Interventions

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Electrical Impedance Tomography record

Monitoring of pleural effusion evacuation by means of EIT

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* mechanical ventilation, presence of pleural effusion, decision of the treating physician to drain it

Exclusion Criteria

* impossibility to apply EIT belt or to find suitable save point for drainage when the EIT belt is attached
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Military University Hospital, Prague

OTHER

Sponsor Role collaborator

Czech Technical University in Prague

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Karel Roubik, Prof., PhD.

Role: PRINCIPAL_INVESTIGATOR

Czech Technical University in Prague

Locations

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The Military University Hospital

Prague, , Czechia

Site Status

Countries

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Czechia

References

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Razazi K, Thille AW, Carteaux G, Beji O, Brun-Buisson C, Brochard L, Mekontso Dessap A. Effects of pleural effusion drainage on oxygenation, respiratory mechanics, and hemodynamics in mechanically ventilated patients. Ann Am Thorac Soc. 2014 Sep;11(7):1018-24. doi: 10.1513/AnnalsATS.201404-152OC.

Reference Type BACKGROUND
PMID: 25079591 (View on PubMed)

Mattison LE, Coppage L, Alderman DF, Herlong JO, Sahn SA. Pleural effusions in the medical ICU: prevalence, causes, and clinical implications. Chest. 1997 Apr;111(4):1018-23. doi: 10.1378/chest.111.4.1018.

Reference Type BACKGROUND
PMID: 9106583 (View on PubMed)

Goligher EC, Leis JA, Fowler RA, Pinto R, Adhikari NK, Ferguson ND. Utility and safety of draining pleural effusions in mechanically ventilated patients: a systematic review and meta-analysis. Crit Care. 2011;15(1):R46. doi: 10.1186/cc10009. Epub 2011 Feb 2.

Reference Type BACKGROUND
PMID: 21288334 (View on PubMed)

Alves SH, Amato MB, Terra RM, Vargas FS, Caruso P. Lung reaeration and reventilation after aspiration of pleural effusions. A study using electrical impedance tomography. Ann Am Thorac Soc. 2014 Feb;11(2):186-91. doi: 10.1513/AnnalsATS.201306-142OC.

Reference Type BACKGROUND
PMID: 24308560 (View on PubMed)

Other Identifiers

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Ventilation-EIT-PE

Identifier Type: -

Identifier Source: org_study_id

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