Risk Factors of Anxiety and Depression in Patients With Herpes Zoster Neuralgia

NCT ID: NCT06449547

Last Updated: 2024-08-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

600 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-06-21

Study Completion Date

2026-12-31

Brief Summary

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The goal of this observational study is to explore risk factors of anxiety and depression in patients with herpes zoster neuralgia, and the changes of certain serum biomarkers and functional brain magnetic resonance images of these patients.

Detailed Description

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Patients with herpes zoster neuralgia will be recruited and take Hospital anxiety depression rating scale (Hospital anxiety and 'scale, HADS) evaluation. According to the HADS Scores, patients will be divided into depression group and no depression, or anxiety group and no anxiety group. The clinical data the of two groups will be collected and statistically analyzed to explore the risk factors of anxiety and depression, including the changes of serum biomarkers and functional brain magnetic resonance imaging in patients with herpes zoster neuralgia accompanying anxiety or depression.

Conditions

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Herpes Zoster

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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patients with anxiety

Patients in this group suffered from herpes zoster neuralgia and had a score more than or equal to 8 for Hospital Anxiety and Depression Scale- Anxiety questionnaire.

Hospital Anxiety and Depression Scale

Intervention Type DIAGNOSTIC_TEST

Hospital Anxiety and Depression Scale questionnaire is used to test patients for anxiety and depression.

patients without anxiety

Patients in this group suffered from herpes zoster neuralgia and had a score less than 8 for Hospital Anxiety and Depression Scale- Anxiety questionnaire.

Hospital Anxiety and Depression Scale

Intervention Type DIAGNOSTIC_TEST

Hospital Anxiety and Depression Scale questionnaire is used to test patients for anxiety and depression.

patients with depression

Patients in this group suffered from herpes zoster neuralgia and had a score more than or equal to 8 for Hospital Anxiety and Depression Scale- Depression questionnaire.

Hospital Anxiety and Depression Scale

Intervention Type DIAGNOSTIC_TEST

Hospital Anxiety and Depression Scale questionnaire is used to test patients for anxiety and depression.

patients without depression

Patients in this group suffered from herpes zoster neuralgia and had a score less than 8 for Hospital Anxiety and Depression Scale- Depression questionnaire.

Hospital Anxiety and Depression Scale

Intervention Type DIAGNOSTIC_TEST

Hospital Anxiety and Depression Scale questionnaire is used to test patients for anxiety and depression.

Interventions

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Hospital Anxiety and Depression Scale

Hospital Anxiety and Depression Scale questionnaire is used to test patients for anxiety and depression.

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

1. Age more than 18 years old
2. Diagnosed as herpes zoster neuralgia
3. Signing informed consent

Exclusion Criteria

1. Unable to complete the scale assessment
2. History of mental illness
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Huazhong University of Science and Technology

OTHER

Sponsor Role lead

Responsible Party

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Wei Mei

Deputy director of anesthesiology

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Yang Shuguang, M.D

Role: PRINCIPAL_INVESTIGATOR

Tongji medical college of Huazhong University of Science and technology

Locations

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Tongji hospital

Wuhan, Hubei, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Yang Shuguang, M.D

Role: CONTACT

(+86)15071078161

Mei wei, M.D, PhD

Role: CONTACT

(+86)13006162508

Facility Contacts

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Yang Shuguang, Master

Role: primary

15071078161

References

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Du J, Sun G, Ma H, Xiang P, Guo Y, Deng Y, Li S, Li X. Prevalence and Risk Factors of Anxiety and Depression in Patients with Postherpetic Neuralgia: A Retrospective Study. Dermatology. 2021;237(6):891-895. doi: 10.1159/000512190. Epub 2020 Dec 16.

Reference Type BACKGROUND
PMID: 33326962 (View on PubMed)

Other Identifiers

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TJ-IRB202401075

Identifier Type: -

Identifier Source: org_study_id

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