Neuropsychological Evaluation of Psychiatric and Neurological Patients

NCT ID: NCT00001192

Last Updated: 2017-07-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

4300 participants

Study Classification

OBSERVATIONAL

Study Start Date

1983-10-18

Study Completion Date

2006-12-20

Brief Summary

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This study will allow researchers to use various types of tests to evaluate cognitive and sensory functions. These tests, referred to as "batteries" will evaluate attention, executive functions, general intellectual functioning, language, memory, motor functions, orientation, personality, selected sensory and perceptual functions, vigilance (alertness), and visual-spatial functions. Children and adult patient will receive different test batteries.

The goals of this research study are to;

1. Create descriptions based on the performance of each patient on the test batteries. Then use this information to relate patient behavior to their neurophysiological, neuroradiological, and biochemical descriptions.
2. Define subgroups of patients based on their neurobehavior in order to decrease the variability of psychiatric diagnoses, treatments, and prognoses.

Detailed Description

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Neuropsychological tests are used to provide an assessment of cognitive functions in patients with idiopathic generalized epileptic (IGE) disorders and their first-degree relatives. The battery comprises tests designed to tap attention, memory, selected sensory and perceptual functions, vigilance, and visual-spatial functions. Modified batteries have been developed for the assessment of children ages 5-8, and children ages 8-16. The data provided by these batteries are compared with genetic profiles of the same participants that have been ascertained from blood samples analyzed by colleagues at the Mount Sinai School of Medicine/Columbia University in New York City.

Conditions

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Anxiety Disorder Head Injury Mood Disorder Schizophrenia Seizures

Eligibility Criteria

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Inclusion Criteria

Patients.

Normal volunteers.

Exclusion Criteria

Subjects over 95 years of age.

Subjects with a history of alcohol or drug abuse, psychopathology, or central nervous system pathology, other than that which defines group membership, may be excluded.
Maximum Eligible Age

95 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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National Institute of Mental Health (NIMH)

NIH

Sponsor Role lead

Locations

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Childrens National Medical Center

Washington D.C., District of Columbia, United States

Site Status

National Institutes of Health Clinical Center, 9000 Rockville Pike

Bethesda, Maryland, United States

Site Status

Henry Ford Health Systems

Detroit, Michigan, United States

Site Status

Mt. Sinai Medical Center

New York, New York, United States

Site Status

Columbia University

New York, New York, United States

Site Status

Genethon

Every Cedex, , France

Site Status

Mosco Research Institute of Psychiatry

Moscow, , Russia

Site Status

Countries

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United States France Russia

References

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Johnstone EC, Owens DG, Bydder GM, Colter N, Crow TJ, Frith CD. The spectrum of structural brain changes in schizophrenia: age of onset as a predictor of cognitive and clinical impairments and their cerebral correlates. Psychol Med. 1989 Feb;19(1):91-103. doi: 10.1017/s0033291700011053.

Reference Type BACKGROUND
PMID: 2727213 (View on PubMed)

Other Identifiers

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83-M-0176

Identifier Type: -

Identifier Source: secondary_id

830176

Identifier Type: -

Identifier Source: org_study_id

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