Emotional Brain Networks & Cognitive Functioning in Depression and Anxiety

NCT ID: NCT03084042

Last Updated: 2018-10-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

105 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-07-31

Study Completion Date

2019-06-30

Brief Summary

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This study aims to 1) examine common and specific emotional and cognitive dysfunctions between Major Depression and generalized anxiety disorder; 2) Examine emotional and cognitive dysfunctions between the two disorders and healthy controls; 3) Examine the biomarkers predicting successful therapy or not.

Detailed Description

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Conditions

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Major Depressive Disorder General Anxiety Disorder

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Depression patients (MDD)

Patients with diagnosis of major depression according to DSM criteria

fMRI

Intervention Type DEVICE

Anxiety patients (GAD)

Patients with generalized anxiety disorder according to DSM criteria

fMRI

Intervention Type DEVICE

Healthy controls

Demographically matched healthy controls.

fMRI

Intervention Type DEVICE

Interventions

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fMRI

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* GAD:

1. Diagnosis of Generalized Anxiety Disorder (GAD) according to DSM V criteria in a structured clinical interview for DSM-V Axis I disorders (SCID I; APA, 2014) and a confirmatory clinical interview
2. Duration of the current episode \> 3 weeks
* MDD:

1. Diagnosis of current major depressive disorder in a structured clinical interview for DSM-V Axis I disorders (SCID I; APA, 2014) and a confirmatory clinical interview
2. Duration of the current episode \> 4 weeks

Exclusion Criteria

* GAD: diagnosis of any other psychiatric Axis I disorder (except GAD) as a principal diagnosis within the past six months
* MDD: diagnosis of any other psychiatric Axis I disorder (except MDD) as a principal diagnosis within the past six months
Minimum Eligible Age

18 Years

Maximum Eligible Age

55 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Sichuan Provincial People's Hospital

OTHER

Sponsor Role collaborator

The Fourth People's Hospital of Chengdu

OTHER

Sponsor Role collaborator

University of Electronic Science and Technology of China

OTHER

Sponsor Role lead

Responsible Party

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Benjamin Becker

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Benjamin Becker, Dr.

Role: PRINCIPAL_INVESTIGATOR

School of Life Science and Technology, University of Electronic Science and Technology of China

Locations

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School of Life Science and Technology, University of Electronic Science and Technology of China

Chengdu, Sichuan, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Benjamin Becker, Dr.

Role: CONTACT

Facility Contacts

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Benjamin Becker, Dr.

Role: primary

Other Identifiers

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UESTC-neuSCAN-23

Identifier Type: -

Identifier Source: org_study_id

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