Brain Network fMRI Analysis in Proprioceptive Training for Chronic Low Back Pain

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

40 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-12-20

Study Completion Date

2028-12-30

Brief Summary

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Through longitudinal analysis of dynamic changes in DMN functional connectivity before and after sensory training intervention, combined with pain behavioral and functional improvement indicators, this study systematically reveals the central neural remodeling patterns in CNLBP and establishes an objective efficacy evaluation system based on multimodal imaging.

Detailed Description

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This phase of the research aims to elucidate the neuroplasticity mechanisms induced by CNLBP treatment, providing a theoretical basis for the future development of personalized rehabilitation protocols based on brain network subtypes, ultimately achieving the clinical goals of reducing pain recurrence rates and improving long-term prognosis in patients.

Conditions

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Brain Network Functional Connectivity

Study Design

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Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Interventions

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Multimodal Imaging Evaluation

Functional connectivity analysis of brain networks based on functional magnetic resonance imaging (fMRI) technology

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Age between 18 and 60 years old;

* Current or past low back pain lasting more than three months; ③ No abnormal sensation or reflex abnormalities in the lower limbs; ④ Able to commit to participating in training three times per week for three months.

Exclusion Criteria

* Fractures, dislocations, structural abnormalities, prior surgery, metal implants, or lumbar disc herniation;

* Comorbidities such as severe cardiovascular diseases, neurological disorders, osteoporosis, or metabolic diseases; ③ Low back pain caused by visceral diseases;

* VAS score (range 1-10) exceeding 8 points;

* Pregnant or lactating women; ⑥ Symptoms of nerve root irritation; ⑦ Recent participation in core stability training.

Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

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Responsibility Role SPONSOR

Central Contacts

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yongxiang li

Role: CONTACT

Phone: 15267370425

Email: [email protected]

yali liu