The Use of Resting State, fMRI and DTI in the Identification of Chronic Pain Conditions
NCT ID: NCT02987933
Last Updated: 2016-12-09
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
40 participants
OBSERVATIONAL
2016-11-30
2018-01-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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CASE_CONTROL
PROSPECTIVE
Study Groups
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Chronic Pain
Adults, \> 6 months duration, daily pain
No interventions assigned to this group
Healthy Normals
Age and gender matched controls
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
20 Years
70 Years
ALL
Yes
Sponsors
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State University of New York at Buffalo
OTHER
Brain Scan Inc.
INDUSTRY
Responsible Party
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Principal Investigators
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David S Wack, Ph.D.
Role: PRINCIPAL_INVESTIGATOR
University at Buffalo: SUNY
Locations
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WNY MRI
Buffalo, New York, United States
Countries
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Central Contacts
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Facility Contacts
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References
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Napadow V, LaCount L, Park K, As-Sanie S, Clauw DJ, Harris RE. Intrinsic brain connectivity in fibromyalgia is associated with chronic pain intensity. Arthritis Rheum. 2010 Aug;62(8):2545-55. doi: 10.1002/art.27497.
Kucyi A, Moayedi M, Weissman-Fogel I, Goldberg MB, Freeman BV, Tenenbaum HC, Davis KD. Enhanced medial prefrontal-default mode network functional connectivity in chronic pain and its association with pain rumination. J Neurosci. 2014 Mar 12;34(11):3969-75. doi: 10.1523/JNEUROSCI.5055-13.2014.
Baliki MN, Geha PY, Apkarian AV, Chialvo DR. Beyond feeling: chronic pain hurts the brain, disrupting the default-mode network dynamics. J Neurosci. 2008 Feb 6;28(6):1398-403. doi: 10.1523/JNEUROSCI.4123-07.2008.
Boeckle M, Schrimpf M, Liegl G, Pieh C. Neural correlates of somatoform disorders from a meta-analytic perspective on neuroimaging studies. Neuroimage Clin. 2016 Apr 10;11:606-613. doi: 10.1016/j.nicl.2016.04.001. eCollection 2016.
Tagliazucchi E, Balenzuela P, Fraiman D, Chialvo DR. Brain resting state is disrupted in chronic back pain patients. Neurosci Lett. 2010 Nov 12;485(1):26-31. doi: 10.1016/j.neulet.2010.08.053. Epub 2010 Aug 26.
Other Identifiers
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BSI001
Identifier Type: -
Identifier Source: org_study_id
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