Decoding Chronic Pain With fMRI

NCT ID: NCT01766973

Last Updated: 2018-06-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

76 participants

Study Classification

OBSERVATIONAL

Study Start Date

2013-04-06

Study Completion Date

2018-06-06

Brief Summary

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Recent evidence suggests that chronic pain is associated with abnormal connectivity between brain regions associated with the processing of pain. We aim to test the diagnostic power of resting state functional magnetic resonance imaging (MRI) to diagnose patients with chronic back pain. Using new methods of image acquisition and analysis we aim to develop a computational method to correctly classify patients and matched control subjects.

Detailed Description

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Conditions

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Chronic Back Pain

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Chronic back pain

Adults, \>6months duration

No interventions assigned to this group

Control

Age and sex matched controls

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* age 18-60
* pain \> 6months
* right-handed
* non-smoking
* mechanical back pain

Exclusion Criteria

* significant neurological or psychiatric disease
* major systemic illness
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Cambridge

OTHER

Sponsor Role lead

Responsible Party

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Dr Ben Seymour

Wellcome Intermediate Clinical Fellow

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Ben Seymour, MRCP PhD

Role: PRINCIPAL_INVESTIGATOR

University of Cambridge

Locations

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Addenbrookes Hospital

Cambridge, , United Kingdom

Site Status

Countries

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United Kingdom

Other Identifiers

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CE-U.NA.NFLT.EGDF

Identifier Type: -

Identifier Source: org_study_id

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