A Novel Neurobehavioral Intervention for Emotion Regulation in Anxiety and Depression Across the Lifespan

NCT ID: NCT01616797

Last Updated: 2018-09-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

68 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-02-28

Study Completion Date

2018-08-31

Brief Summary

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The research proposes to use an innovative solution to shape brain circuits that support executive function and emotion reactivity -using targeted neurobehavioral intervention.

Detailed Description

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Participants will be recruited locally in the San Francisco Bay area with certain symptoms of anxiety and depression. They will complete a clinical assessment and then take part in a cognitive-emotion training delivered online.

Conditions

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Depression, Anxiety Cognitive Training Emotion Training Emotion Regulation

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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Computerized intervention

Participants will be asked to visit a customized website and engage in computerized exercises. Cognitive and emotion training games.

Group Type EXPERIMENTAL

Computerized neurobehavioral intervention

Intervention Type BEHAVIORAL

Participants will complete the intervention by logging into a secure online website and complete computerized neurobehavioral tasks. Tasks will train the following - cognitive control, working memory and task shifting with two different tasks that engage these skills and positivity biases.

Control

Participants will be asked to visit a customized website and engage in computerized games.

Group Type SHAM_COMPARATOR

Computerized neurobehavioral intervention

Intervention Type BEHAVIORAL

Participants will complete the intervention by logging into a secure online website and complete computerized neurobehavioral tasks. Tasks will train the following - cognitive control, working memory and task shifting with two different tasks that engage these skills and positivity biases.

Interventions

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Computerized neurobehavioral intervention

Participants will complete the intervention by logging into a secure online website and complete computerized neurobehavioral tasks. Tasks will train the following - cognitive control, working memory and task shifting with two different tasks that engage these skills and positivity biases.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Diagnosis of depression on the SCID, a total Ham-D≥16 and Ham-D anxiety/somatization subscale ≥ 7.

Exclusion Criteria

* Current medication for psychiatric disorders
* Pregnant females
* Head trauma or injury that resulted in loss of consciousness
* MRI contraindication
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Stanford University

OTHER

Sponsor Role lead

Responsible Party

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Amit Etkin

Principle Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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VA Palo Alto Health Care System (VAPAHCS)

Palo Alto, California, United States

Site Status

Stanford University Department of Pscyhiatry and Behavioral Sciences

Stanford, California, United States

Site Status

Countries

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United States

Other Identifiers

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IRB-24813

Identifier Type: -

Identifier Source: org_study_id

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