Seminal Levels of PGK2 and ACRV1 as Predictors of Micro-TESE Results in NOA

NCT ID: NCT06307639

Last Updated: 2024-03-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

64 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-04-01

Study Completion Date

2026-04-01

Brief Summary

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* Measurement of PGK2 and ACRV1 levels in the semen of infertile males undergoing testicular sperm extraction (TESE).
* Correlate seminal levels of PGK2 and ACRV1 with sperm retrieval results and histopathology analysis of testicular biopsy samples.

Detailed Description

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Conditions

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Male Infertility Due to Azoospermia

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Interventions

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Measurement of PGK2 and ACRV1 levels in the semen of infertile males undergoing testicular sperm extraction (TESE).

Measurement of PGK2 and ACRV1 levels in the semen of infertile males undergoing testicular sperm extraction (TESE).

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Infertile males with normal volume, functional (non-obstructive) azoospermia.
* Age: 18-45 years

Exclusion Criteria

* Patients with proven obstructive azoospermia.
* Cryptorchidism.
* Testicular Agenesis and testicular atrophy.
* Patient with exposure to gonadal toxins like chemotherapy, radiotherapy, and alkylating agents.
Minimum Eligible Age

18 Years

Maximum Eligible Age

45 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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Assiut University

OTHER

Sponsor Role lead

Responsible Party

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Muhammad Yousef Muhammad Swifee

Assistant lecturer of Andrology ,Sexology and STIs

Responsibility Role PRINCIPAL_INVESTIGATOR

Other Identifiers

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MYMSwifee

Identifier Type: -

Identifier Source: org_study_id

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