Effects of Different Fresh Gas Flows on Carboxyhemoglobin Levels and Postoperative Patient Outcomes in Pediatric Cardiovascular Surgery
NCT ID: NCT06097806
Last Updated: 2024-05-21
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
40 participants
OBSERVATIONAL
2024-06-01
2025-11-01
Brief Summary
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In studies conducted in different fresh gas flows, it has been observed that CO, which is thought to accumulate in the body by rebreathing in a closed circuit, increases as a result of the chemical interaction and dry CO2 absorbent. However, there is no evidence in these studies that low-flow anesthesia increases CO accumulation and alters hemodynamics.
In our clinic, low-flow and high-flow anesthesia technics are both being used. In this study, we aimed to evaluate the effects of high- and low-flow sevoflurane anesthesia applied with a closed system on perioperative carboxyhemoglobin (COHb) levels and hemodynamic system in pediatric cardiovascular surgery cases.
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Detailed Description
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Conditions
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Study Design
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OTHER
PROSPECTIVE
Study Groups
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Low-flow anesthesia group
In this group, ventilation parameters is adjusted to have fresh gas flow/minute ventilation ratio below 0.5
low and high flow
low and high flow anesthesia are both being used. The effects of different gas flows will be evaluated.
High-flow anesthesia group
In this group, ventilation parameters is adjusted to have fresh gas flow/minute ventilation ratio above 1.0
low and high flow
low and high flow anesthesia are both being used. The effects of different gas flows will be evaluated.
Interventions
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low and high flow
low and high flow anesthesia are both being used. The effects of different gas flows will be evaluated.
Eligibility Criteria
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Inclusion Criteria
* American Society of Anesthesiology (ASA) score II ve III patients
Exclusion Criteria
* Patients who need mechanical ventilation or any respiratory support before the operation
* Patients with left to right shunt
* cyanotic patients
* Patients younger than 2 months and older than 7 years
2 Months
7 Years
ALL
No
Sponsors
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Başakşehir Çam & Sakura City Hospital
OTHER_GOV
Responsible Party
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Selin Saglam
Specialist
Locations
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Basaksehir Cam and Sakura City Hospital
Istanbul, , Turkey (Türkiye)
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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Başakşehir Çam and Sakura
Identifier Type: -
Identifier Source: org_study_id
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