Low Flow Anesthesia Without Initial High Flow Phase

NCT ID: NCT03955406

Last Updated: 2019-07-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

80 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-05-22

Study Completion Date

2019-07-02

Brief Summary

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The aim of the study is to compare the effectiveness of conventional low flow anesthesia (LFA) with initial high fresh gas flow ( 4L/min) for 10 minutes and LFA with fixed fresh gas flow rate (1L/min).

Detailed Description

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Conditions

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Low Flow Anesthesia Volatile Anesthetic Consumption

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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Conventional group

After standart intravenous anesthesia induction end endotracheal intubation desflurane vaporizer will be set at 6% with fresh gas flow rate 4 L/min (50% O2, 50% air) until the EtAA concentration reaches 0.7 MAC (minimum alveolar concentration) Then, the desflurane vaporizer will be at a 1% higher value than the EtAA concentration required to achieve 0.7 MAC. And after 10 minutes fresh gas flow rate will be reduced to 1L/min.

Group Type ACTIVE_COMPARATOR

Conventional Low flow Anesthesia

Intervention Type PROCEDURE

During the initial wash-in period 4 L/min Fresh gas flow will be used.

Fixed Fresh Gas Flow Rate group

After standart intravenous anesthesia induction end endotracheal intubation desflurane vaporizer will be set at 18% with fresh gas flow rate 1 L/min (50% O2, 50% air) until the EtAA concentration reaches 0.7 MAC (minimum alveolar concentration) Then, the desflurane vaporizer will be at a 2% higher value than the EtAA concentration required to achieve 0.7 MAC.

Group Type ACTIVE_COMPARATOR

Low Flow Anesthesia with fixed fresh gas flow rate

Intervention Type PROCEDURE

Fresh gas flow rate will be 1 L/min throughout the procedure.

Interventions

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Conventional Low flow Anesthesia

During the initial wash-in period 4 L/min Fresh gas flow will be used.

Intervention Type PROCEDURE

Low Flow Anesthesia with fixed fresh gas flow rate

Fresh gas flow rate will be 1 L/min throughout the procedure.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* ASA 1-3
* scheduled for surgery under general anesthesia with endotracheal intubation

Exclusion Criteria

* hemodynamic instability
* emergency cases
* expected anesthesia duration \< 60 min
* patient refusal
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Kahramanmaras Sutcu Imam University

OTHER

Sponsor Role lead

Responsible Party

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MAHMUT ARSLAN

Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Kahramanmaras Sutcu Imam University

Kahramanmaraş, In the USA Or Canada, Please Select..., Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

Related Links

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Other Identifiers

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KSU 2017-15

Identifier Type: -

Identifier Source: org_study_id

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