Low and Moderete Flow Anaesthesia on Haemodynamics

NCT ID: NCT06871371

Last Updated: 2025-03-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

76 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-03-15

Study Completion Date

2025-04-15

Brief Summary

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The study topic investigates the potential advantages of low-flow anesthesia in terms of physiological protection and resource saving.

Detailed Description

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The study aims to compare the effects of low and normal flow sevoflurane anesthesia on the frontal QRS-T angle and cerebral oxygenation in laparoscopic cholecystectomy surgery. The primary objective was to evaluate the effects of low-flow anesthesia on hemodynamic stability and arrhythmia risk; the secondary objective was to compare the total sevoflurane consumption in both methods.

Conditions

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Hemodynamics Instability Arrhythmias Cardiac Cerebral Oxygenation

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SCREENING

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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low flow anesthesia

Maintenance of anaesthesia with low-flow anaesthesia

Group Type ACTIVE_COMPARATOR

Sevoflurane (Volatile Anesthetic)

Intervention Type DEVICE

Both groups will be given sevoflurane and one group will be given low current anesthesia and the other group will be given medium flow anesthesia.

low- medium flow anesthetic machine

Intervention Type DEVICE

The study aims to compare the effects of low and normal flow sevoflurane anesthesia on the frontal QRS-T angle and cerebral oxygenation in laparoscopic cholecystectomy surgery.

Medium Flow Anesthesia

Maintenance of anaesthesia with medium-flow anaesthesia

Group Type ACTIVE_COMPARATOR

Sevoflurane (Volatile Anesthetic)

Intervention Type DEVICE

Both groups will be given sevoflurane and one group will be given low current anesthesia and the other group will be given medium flow anesthesia.

low- medium flow anesthetic machine

Intervention Type DEVICE

The study aims to compare the effects of low and normal flow sevoflurane anesthesia on the frontal QRS-T angle and cerebral oxygenation in laparoscopic cholecystectomy surgery.

Interventions

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Sevoflurane (Volatile Anesthetic)

Both groups will be given sevoflurane and one group will be given low current anesthesia and the other group will be given medium flow anesthesia.

Intervention Type DEVICE

low- medium flow anesthetic machine

The study aims to compare the effects of low and normal flow sevoflurane anesthesia on the frontal QRS-T angle and cerebral oxygenation in laparoscopic cholecystectomy surgery.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* being ASA1-2 status
* between the ages of 18-70
* who are planned for laparoscopic cholecystectomy

Exclusion Criteria

* Patients who refuse to give informed consent
* Pregnant and breastfeeding patients
* Morbidly obese patients (Body mass index over 40)
* Patients with uncontrolled diabetes mellitus, with serious cardiovascular, pulmonary, renal, hepatic disease, obstructive sleep apnea, with electrolyte imbalance- Those with a history of alcohol or drug abuse, with perioperative hemodynamic instability
* Patients using drugs known to prolong myocardial repolarization
* inability to increase SPO2 above 95 despite necessary intervention
Minimum Eligible Age

17 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Umraniye Education and Research Hospital

OTHER_GOV

Sponsor Role lead

Responsible Party

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Senay Goksu

specialist

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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SENAY GOKSU, MD

Role: PRINCIPAL_INVESTIGATOR

UMRANIYE E R HOSPITAL

Locations

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Umraniye Education and research hospital

Istanbul, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

Central Contacts

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senay goksu, specialist doctor

Role: CONTACT

+905337144852

Other Identifiers

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LFATUGCE

Identifier Type: -

Identifier Source: org_study_id

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