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The Affecting Factors on Airway Temperature and Moisture

NCT ID: NCT04204746

Last Updated: 2019-12-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

240 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-04-01

Study Completion Date

2018-04-01

Brief Summary

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There is no literature information about the flow rate of fresh gas mixture (air+O2) in the patients who underwent general anesthesia. Different flow rates of fresh gas mixture are used in both the investigator's hospital and the experiences of the anesthesiologists. It is aimed to study the effects of different fresh gas flow rates on the rate of temperature and moisture of the airway of patients who underwent general anesthesia.

Detailed Description

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Under physiological conditions, inhaled air is heated and humidified as it passes through the nose and upper airways until reaching the alveoli. This mechanism is bypassed by endotracheal intubation. Ventilation with dry and cold compressed gases leads to loss of water and heat from the respiratory tract. Drying of the respiratory tract can lead to destruction of the cilia and mucous membranes, resulting in decreased mucociliary transport and increased concentration of secretions.There is no definitive literature on fresh gas mix (oxygen + air) flow rates in patients under general anesthesia. This study aimed to investigate whether two fresh gas flow rates routinely employed in the authors' practice affected airway temperature and humidity.

Conditions

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General Anesthesia

Keywords

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general anesthesia fresh gas moisture temperature respiratory circuit

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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3 lt/min

Patients in the study were divided into two main groups according to the standard fresh gas flow administered (3-6 L/min). Each main group was then divided into subgroups as follows: sevoflurane + remifentanil, desflurane + remifentanil, or propofol + remifentanil (TIVA). These six groups were further divided into two groups according to use or non-use of a heat and moisture exchanger (HME) filter.

We will observe and evaluate the temperature and moisture in the respiratory circuit by a thermo-hygrometer.

Intervention Type OTHER

6 lt/min

Patients in the study were divided into two main groups according to the standard fresh gas flow administered (3-6 L/min). Each main group was then divided into subgroups as follows: sevoflurane + remifentanil, desflurane + remifentanil, or propofol + remifentanil (TIVA). These six groups were further divided into two groups according to use or non-use of a heat and moisture exchanger (HME) filter.

We will observe and evaluate the temperature and moisture in the respiratory circuit by a thermo-hygrometer.

Intervention Type OTHER

Interventions

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We will observe and evaluate the temperature and moisture in the respiratory circuit by a thermo-hygrometer.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

Patients aged 18-65 years underwent general anesthesia -

Exclusion Criteria

\-
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Selcuk University

OTHER

Sponsor Role lead

Responsible Party

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Ozkan Onal

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Ozkan Onal, Professor

Role: PRINCIPAL_INVESTIGATOR

Selcuk University

References

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Ozcan IG, Onal O, Ozdemirkan A, Saltali A, Sari M. Effects of different fresh gas flows and different anesthetics on airway temperature and humidity in surgical patients: a prospective observational study. Med Gas Res. 2022 Jul-Sep;12(3):83-90. doi: 10.4103/2045-9912.330691.

Reference Type DERIVED
PMID: 34854418 (View on PubMed)

Other Identifiers

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E.90598

Identifier Type: -

Identifier Source: org_study_id