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PCV vs VCV in Low-Flow Anesthesia

NCT ID: NCT07305129

Last Updated: 2025-12-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

40 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-07-01

Study Completion Date

2025-08-01

Brief Summary

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The aim of this observational study is to investigate the effects of ventilation modes on intraoperative and postoperative lung functions in patients under general anesthesia.

This study aimed to compare the effects of low-flow anesthesia on intraoperative respiratory mechanics and early postoperative pulmonary function between PCV and VCV in ASA I-II adult patients.

Detailed Description

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Studies comparing the effects of pressure-controlled ventilation (PCV) and volume-controlled ventilation (VCV) on lung function under low-flow conditions are limited. In this study, the effects of PCV and VCV on intraoperative respiratory mechanics and early postoperative pulmonary function were investigated during low-flow anesthesia in ASA I-II adult patients undergoing routine anesthesia procedures.

Conditions

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ASA Class I/II Patients General Anesthetic Low Flow Anesthesia

Keywords

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low-flow anesthesia pressure-controlled ventilation volume-controlled ventilation respiratory mechanics peak inspiratory pressure pulmonary function

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

RETROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

\- age 18-65 years and American Society of Anesthesiologists (ASA) physical status I-II.

Exclusion Criteria

* morbid obesity (BMI \> 35 kg/m²),
* scoliosis or thoracic deformity,
* restrictive or obstructive lung disease,
* prior thoracic or upper abdominal surgery,
* history of major thoracic trauma or congenital chest wall anomaly,
* active smoking or chronic use of corticosteroids,
* β-agonists, bronchodilators, or antihistamines,
* anticipated difficult airway
* severe hypoxemia (SpO₂ \< 90%) during induction.
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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HULYA TOPCU, MD

OTHER

Sponsor Role lead

Responsible Party

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HULYA TOPCU, MD

Assoc. Prof. MD

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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Hitit University Erol Olçok Training and Research Hospital

Çorum, Çorum, Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

Other Identifiers

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hulya topcu

Identifier Type: OTHER

Identifier Source: secondary_id

serhat ozciftci

Identifier Type: OTHER

Identifier Source: secondary_id

2023-64

Identifier Type: -

Identifier Source: org_study_id