Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
20 participants
INTERVENTIONAL
2023-10-15
2024-03-01
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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Experimental neurofeedback intervention
In an approximately 30-minute training session, participants receive activity feedback from a midbrain region involved in reward processing and gaming addiction. Feedback will be presented in the form of a thermometer/bar in the middle of the screen and updated every two seconds. They will be trained to down-regulate the activity in this region with the help of this feedback using cognitive strategies. This down-regulation training is believed to be beneficial to addictive behaviors by the investigators.
Neurofeedback training
Neurofeedback training is a type of non-invasive brain modulation technique that enables individuals to self-regulate brain activity patterns by providing them feedback on specific activity measures. Effective self-regulation is often linked to changes in cognition, behavior, and clinical symptoms.
Sham feedback intervention
In an approximately 30-minute training session, participants receive activity feedback from a brain region irrelevant to reward processing or gaming addictive behavior. The feedback presentation form and task instructions will be the same as for the experimental group. Based on the functional role of the feedback region, the investigators do not believe this feedback training will change the addictive behaviors of the participants who receive this intervention.
Sham feedback training
A controlled form of neurofeedback training that provides feedback irrelevant to the targeted mental process.
Interventions
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Neurofeedback training
Neurofeedback training is a type of non-invasive brain modulation technique that enables individuals to self-regulate brain activity patterns by providing them feedback on specific activity measures. Effective self-regulation is often linked to changes in cognition, behavior, and clinical symptoms.
Sham feedback training
A controlled form of neurofeedback training that provides feedback irrelevant to the targeted mental process.
Eligibility Criteria
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Inclusion Criteria
* First language is Chinese (Mandarin)
* Right-handed
* Have played the mobile game "King of Glory" for more than 3 years
* Ability to give informed consent
* Normal or corrected-to-normal vision
Exclusion Criteria
* Any history of psychological or neurological disorder
* Any MRI contraindication
* Currently on a psychotropic medication
* Any history of substance dependence
* Any history of brain injury or surgery
18 Years
28 Years
ALL
Yes
Sponsors
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University of Macau
OTHER
Responsible Party
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Principal Investigators
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Zhen Yuan, Ph.D
Role: STUDY_DIRECTOR
University of Macau
Locations
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Centre for Cognitive and Brain Sciences, University of Macau
Taipa, , Macau
Countries
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References
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Gu A, Chan CL, Xu X, Dexter JP, Becker B, Zhao Z. Real-Time fMRI Neurofeedback Modulation of Dopaminergic Midbrain Activity in Young Adults With Elevated Internet Gaming Disorder Risk: Randomized Controlled Trial. J Med Internet Res. 2025 Jan 29;27:e64687. doi: 10.2196/64687.
Other Identifiers
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BSERE23-APP004-ICI
Identifier Type: -
Identifier Source: org_study_id
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