Cortical Excitability Using Transcranial Magnetic Stimulation and Neuronavigation Device

NCT ID: NCT02596789

Last Updated: 2017-05-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

75 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-06-30

Study Completion Date

2016-06-30

Brief Summary

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This study has two main goals :

* to investigate the impact of aging on cortical excitability (CE)
* to investigate the impact of "state dependency" on CE, using a cognitive task and an emotional one.

A Neuronavigation system of transcranial magnetic stimulation is used, and electromyographic response are recorded.

Detailed Description

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Conditions

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Healthy Volunteers

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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state dependency TMS

TMS performed at rest and during a cognitive/emotional task

Group Type OTHER

TMS "Magpro®, Magventure Inc" device

Intervention Type DEVICE

Interventions

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TMS "Magpro®, Magventure Inc" device

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* male or female
* age 18-75
* signed informed consent
* normal physical examination

Exclusion Criteria

* less 18 or more 75 years of age
* contra indication to TMS: epilepsia or seizures, metallic head devices, cardiac pacemaker, pregnancy, jet lag or severe insomnia the night before
* severe physical disease
* treatment with psychotropic drugs
* overt psychiatric disease
* alcohol consumption before the examination
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University Hospital, Grenoble

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Thierry BOUGEROL, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Grenoble

Locations

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Department of Psychiatry & Neurology - University Hospital Grenoble

Grenoble, , France

Site Status

Countries

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France

Other Identifiers

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2012-A00316-37

Identifier Type: -

Identifier Source: org_study_id

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