Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
43 participants
INTERVENTIONAL
2012-03-31
2014-09-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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Emotion network up-regulation
Participants use fMRI-based neurofeedback to train the upregulation of brain areas that respond to positive affective pictures (as identified during a functional localiser scan).
fMRI-based neurofeedback
5 sessions lasting one hour each
Place processing network up-regulation
Participants use fMRI-based neurofeedback to train the upregulation of brain areas that respond to place and house pictures (as identified during a functional localiser scan).
fMRI-based neurofeedback
5 sessions lasting one hour each
Interventions
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fMRI-based neurofeedback
5 sessions lasting one hour each
Eligibility Criteria
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Inclusion Criteria
* stable antidepressant dose medication
Exclusion Criteria
* Current substance abuse
* Current psychotherapy or other specific intervention
18 Years
ALL
No
Sponsors
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Medical Research Council
OTHER_GOV
National Institute for Social Care and Health Research
UNKNOWN
Cardiff University
OTHER
Responsible Party
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David Linden
Professor of Translational Neuroscience
Principal Investigators
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David E Linden, MD
Role: PRINCIPAL_INVESTIGATOR
Cardiff University
Locations
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CUBRIC
Cardiff, Wales, United Kingdom
School of Medicine, Cardiff University
Cardiff, Wales, United Kingdom
Countries
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References
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Johnston SJ, Boehm SG, Healy D, Goebel R, Linden DE. Neurofeedback: A promising tool for the self-regulation of emotion networks. Neuroimage. 2010 Jan 1;49(1):1066-72. doi: 10.1016/j.neuroimage.2009.07.056. Epub 2009 Jul 29.
Johnston S, Linden DE, Healy D, Goebel R, Habes I, Boehm SG. Upregulation of emotion areas through neurofeedback with a focus on positive mood. Cogn Affect Behav Neurosci. 2011 Mar;11(1):44-51. doi: 10.3758/s13415-010-0010-1.
Fovet T, Jardri R, Linden D. Current Issues in the Use of fMRI-Based Neurofeedback to Relieve Psychiatric Symptoms. Curr Pharm Des. 2015;21(23):3384-94. doi: 10.2174/1381612821666150619092540.
Other Identifiers
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G 1100629
Identifier Type: OTHER_GRANT
Identifier Source: secondary_id
HS/10/25
Identifier Type: OTHER_GRANT
Identifier Source: secondary_id
11/WA/0106
Identifier Type: OTHER
Identifier Source: secondary_id
SPON927-11
Identifier Type: -
Identifier Source: org_study_id
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