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Brain Imaging of Psychotherapy for Depression

NCT ID: NCT00609453

Last Updated: 2012-10-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

27 participants

Study Classification

INTERVENTIONAL

Study Start Date

2006-10-31

Study Completion Date

2008-01-31

Brief Summary

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The goal of the proposed research is to examine the neural correlates of depressive symptom reduction in individuals with major depressive disorder using functional magnetic resonance imaging (fMRI), and to compare results to those obtained from a nondepressed control group.

Detailed Description

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Conditions

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Major Depressive Disorder

Keywords

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Control participants

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

SINGLE_GROUP

Blinding Strategy

NONE

Study Groups

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1

Individuals with major depressive disorder receiving therapy

Group Type EXPERIMENTAL

Brief Behavioral Activation Treatment for Depression

Intervention Type BEHAVIORAL

Weekly individual therapy sessions

Interventions

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Brief Behavioral Activation Treatment for Depression

Weekly individual therapy sessions

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* For group 1: Diagnosis of current depression and no other current Axis I psychiatric disorder
* For group 1: Hamilton Depression Rating Scale score of 15 or greater

Exclusion Criteria

* A history of serious head injury or neurological disease or psychosis
* Current use of psychoactive medications
* Factors that could affect MRI safety including current or planned pregnancy
* For group 2: current Axis I psychiatric disorder, as assessed by structured clinical interview
Minimum Eligible Age

21 Years

Maximum Eligible Age

55 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of North Carolina, Chapel Hill

OTHER

Sponsor Role lead

Responsible Party

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Gabriel Dichter

Associate Professor of Psychiatry

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Gabriel S Dichter, PhD

Role: PRINCIPAL_INVESTIGATOR

University of North Carolina, Chapel Hill

Locations

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Duke-UNC Brain Imaging and Analysis Center

Durham, North Carolina, United States

Site Status

Countries

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United States

Other Identifiers

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NIMH R03 MH078145

Identifier Type: -

Identifier Source: secondary_id

05-2605

Identifier Type: -

Identifier Source: org_study_id