Level of DNA-fragmentation Before and After Antioxidant-based Therapies in Male Infertility
NCT ID: NCT06050031
Last Updated: 2024-05-08
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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NOT_YET_RECRUITING
78 participants
OBSERVATIONAL
2024-05-31
2025-12-31
Brief Summary
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Detailed Description
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The primary objective of the study is to assess the effectiveness of 3 months of antioxidant-based therapy on changing patients' DFI level.
The objective of the study is to assess the effect of 3 months of antioxidant-based therapy on the level of DFI. We are primarily interested in testing whether the treatment effectiveness (i.e. the change in DFI level) depends on the initial level (i.e. before treatment) and treatment adherence.
The data will be collected by the physicians and added to the REDcap study registry. Access to the total data set is only permitted for the principal investigator.
Conditions
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Study Design
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COHORT
PROSPECTIVE
Interventions
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Intake of antioxidant supplement
All participants will supplent oral antioxidants (individual or combined which can be obtained without prescription, and which are not regulated as a pharmaceutical drug) over three months.
Eligibility Criteria
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Inclusion Criteria
* Written consent
* Men with infertility problems who want to start an infertility treatment with their partner
Exclusion Criteria
* Intake of prescribed medications
* Exposure to toxins
* Chronic diseases
18 Years
60 Years
MALE
No
Sponsors
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Janna Pape
OTHER
Responsible Party
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Janna Pape
Principal Investigator, Dr. med. Janna Pape
Principal Investigators
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Michael von Wolff, Prof
Role: STUDY_CHAIR
Universitätsklinik fur Frauenheilkunde, Inselspital Bern
Central Contacts
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Other Identifiers
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2023-00611
Identifier Type: -
Identifier Source: org_study_id
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