The Paternal Clock: Uncovering the Consequences of Advanced Paternal Age on Sperm DNA Fragmentation
NCT ID: NCT05894356
Last Updated: 2024-02-20
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
4250 participants
OBSERVATIONAL
2023-06-10
2024-01-30
Brief Summary
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Recent research suggests that advanced paternal age (APA) may lead to DNA damage in sperm, however the precise age at which this risk becomes apparent has not yet been clearly defined, necessitating the identification of the point in time at which high SDF levels occur. With the help of this knowledge, male infertility can be diagnosed with greater accuracy, and infertile couples can receive appropriate care.
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Detailed Description
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Conditions
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Study Design
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COHORT
RETROSPECTIVE
Study Groups
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Men undergoing sperm DNA fragmentation test
Men presenting at the clinic for infertility evaluation
Study chart review
Evaluation of 4250 sperm DNA fragmentation samples with the goal of defining a cut-off age beyond which SDF levels increase significantly
Interventions
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Study chart review
Evaluation of 4250 sperm DNA fragmentation samples with the goal of defining a cut-off age beyond which SDF levels increase significantly
Eligibility Criteria
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Inclusion Criteria
18 Years
MALE
No
Sponsors
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Clinique Ovo
INDUSTRY
Responsible Party
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Principal Investigators
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Jacques Kadoch, MD
Role: PRINCIPAL_INVESTIGATOR
Clinique Ovo
Locations
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Clinique Ovo
Montreal, Quebec, Canada
Countries
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Other Identifiers
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3287
Identifier Type: -
Identifier Source: org_study_id
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