Effect of Two Doses of Coenzyme Q10 on Seminal Fluid and Semen Antioxidant Status
NCT ID: NCT03850561
Last Updated: 2019-02-22
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
65 participants
INTERVENTIONAL
2018-06-01
2019-01-25
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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Coenzyme Q10 200
Coenzyme Q10 200mg/day for 3 months
Coenzyme Q10 200
Coenzyme Q10 200 mg/day
Coenzyme Q10 400
Coenzyme Q10 400mg/day for 3 months
Coenzyme Q10 400
Coenzyme Q10 400 mg/day
Interventions
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Coenzyme Q10 200
Coenzyme Q10 200 mg/day
Coenzyme Q10 400
Coenzyme Q10 400 mg/day
Eligibility Criteria
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Inclusion Criteria
Oligoasthenoteratospermia was diagnosed by semen analysis showing abnormal sperm concentration (\<15 million/ml), progressive motility (\<32%), total motility (\<40%) and morphology (\<30% WHO criteria) as defined by WHO manual for semen analysis 2010
Exclusion Criteria
* Varicocele,
* Genital tract infection,
* Cryptorchidism,
* Testicular trauma or scrotal surgery,
* Endocrine disorder,
* Systemic illness,
* Smoking
* The presence of female factor
18 Years
MALE
No
Sponsors
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University of Sumer
OTHER
Responsible Party
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Dr. Ahmed T Alahmar
Principal Investigator
Principal Investigators
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Ahmed T Alahmar, MBChB, MSC
Role: PRINCIPAL_INVESTIGATOR
University of Sumer, Iraq
Locations
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Fertility Unit, Babyl
Hillah, , Iraq
Countries
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References
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Alahmar AT. The effects of oral antioxidants on the semen of men with idiopathic oligoasthenoteratozoospermia. Clin Exp Reprod Med. 2018 Jun;45(2):57-66. doi: 10.5653/cerm.2018.45.2.57. Epub 2018 Jun 29.
Alshahrani S, Aldossari K, Al-Zahrani J, Gabr AH, Henkel R, Ahmad G. Interpretation of semen analysis using WHO 1999 and WHO 2010 reference values: Abnormal becoming normal. Andrologia. 2018 Mar;50(2). doi: 10.1111/and.12838. Epub 2017 Aug 3.
Nadjarzadeh A, Shidfar F, Amirjannati N, Vafa MR, Motevalian SA, Gohari MR, Nazeri Kakhki SA, Akhondi MM, Sadeghi MR. Effect of Coenzyme Q10 supplementation on antioxidant enzymes activity and oxidative stress of seminal plasma: a double-blind randomised clinical trial. Andrologia. 2014 Mar;46(2):177-83. doi: 10.1111/and.12062. Epub 2013 Jan 7.
Other Identifiers
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EC/2018/8878
Identifier Type: -
Identifier Source: org_study_id
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