Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE2
71 participants
INTERVENTIONAL
2009-12-31
2010-11-30
Brief Summary
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Detailed Description
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Sperm DNA fragmentation was evaluated by Terminal deoxyribonucleotidyltransferase-mediated dUTP nick-end labeling assay (TUNEL) before and after treatment. No differences in basic sperm parameters were found between the Ginger treatment and the placebo group before or after treatment. However, the percentage of DNA-fragmented spermatozoa was markedly reduced (P\< .005) in the Ginger treatment group after the treatment as compared with the pretreatment values). No difference in the pretreatment and post treatment incidence of sperm DNA fragmentation was observed in the placebo group. These data show that sperm DNA damage can be efficiently treated with oral Ginger extract administered during a relatively short time period.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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ginger
The patients with infertility that underwent oral administration of ginger.
oral administration of ginger
Oral administration of ginger in patients with infertility.
Placebo
The patients with infertility that receive placebo.
Placebo
Interventions
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oral administration of ginger
Oral administration of ginger in patients with infertility.
Placebo
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* history of cigarette smoking.
20 Years
50 Years
MALE
Yes
Sponsors
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Royan Institute
OTHER_GOV
Responsible Party
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Principal Investigators
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Hamid Gourabi, PhD
Role: STUDY_CHAIR
Head of Royan Institute
Ali DaliriHampa, MD
Role: STUDY_DIRECTOR
Department of Andrology, Reproductive Biomedicine Center, Royan Institute for Reproductive Biomedicine
Eyed Jalil Hosseini, MD
Role: STUDY_DIRECTOR
Department of Andrology, Reproductive Biomedicine Center, Royan Institute for Reproductive Biomedicine
Hani Department of Andrology, Reproductive Biomedicine Center, Roya, MSc
Role: PRINCIPAL_INVESTIGATOR
Department of Andrology, Reproductive Biomedicine Center, Royan Institute for Reproductive Biomedicine
Locations
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Royan Institute
Tehran, , Iran
Countries
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Related Links
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Related Info
Other Identifiers
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royan-Emb-017
Identifier Type: -
Identifier Source: org_study_id
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