Testicular Versus Ejaculated Spermatozoa for IVF/ICSI in Men With High Sperm DNA Damage
NCT ID: NCT02058082
Last Updated: 2014-02-07
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
COMPLETED
NA
25 participants
INTERVENTIONAL
2005-06-30
2011-12-31
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
In Vitro Fertilisation Versus Intracytoplasmic Sperm Injection in Patients Without Severe Male Factor Infertility
NCT04128904
Comparison of ICSI Outcomes in Cycles Using Testicular and Ejaculate Sperm From Couples With High SDF
NCT04795440
Testicular Sperm Aspiration (TESA) vs. Microfluidic Sperm Separation (MSS)
NCT05866484
ICSI Versus Conventional IVF in Non-male Factor Couples
NCT03428919
Sperm DNA Damage to Intracytoplasmic Sperm Injection Outcome
NCT03129243
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
ejaculated sperm
Intracytoplasmic sperm injection (ICSI) cycles using ejaculated sperm
Intracytoplasmic sperm injection
testicular extracted sperm
Intracytoplasmic sperm injection (ICSI) cycles using testicular extracted sperm
Intracytoplasmic sperm injection
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
Intracytoplasmic sperm injection
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* be considered infertile (\>1 year of unsuccessful attempts of conception
* Any race
* Male partner with persistent sperm DNA damage, DFI\>=30%
* candidates for intracytoplasmic sperm injection (ICSI)
Exclusion Criteria
* female partner older than 38 years
* male or female patients with genetic abnormalities
* patients unable or unwilling to give consent after properly informed
* couples unsuitable for IVF/ICSI
* male patients in whom testicular procedures were contraindicated
18 Years
MALE
No
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
Mount Sinai Hospital, Canada
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Kirk Lo
Associate Professor, Division Urology Mount Sinai Hospital, University Toronto
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
Kirk C. Lo, MD
Role: PRINCIPAL_INVESTIGATOR
MOUNT SINAI HOSPITAL
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
Sperm DNA damage study
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.