Timing of Oocyte Retrieval and Micro Testicular Sperm Extraction

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

129 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-11-15

Study Completion Date

2025-11-30

Brief Summary

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This is a retrospective study to assess outcomes of micro-TESE performed 24 or 48 hours before oocyte retrieval and ICSI.

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Detailed Description

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This retrospective study evaluates patients undergoing ICSI following micro-TESE. Participants are assigned to two groups based on the interval between sperm extraction and oocyte retrieval (24 vs. 48 hours). Clinical and embryological outcomes from the first embryo transfer will be assessed.

Conditions

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Microdissection Testicular Sperm Extraction

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Men who underwent a micro-TESE at the OVO clinic from June 2015 to January 2025.
* Patients with non-obstructive azoospermia (NOA), (absence of spermatozoa in multiple semen analyses)
* Patients with cryptozoospermia, (presence of a small number of spermatozoa detectable only after semen centrifugation)
* Patients with oligoasthenoteratozoospermia (OAT), (sperm concentration of less than 15 million/mL, reduced motility and abnormal morphology)

Exclusion Criteria

* Patients who did not have any sperm noted following micro-TESE
* Use of donor sperm or oocytes
* Frozen sperm or oocytes
* Same day oocyte retrieval and sperm extraction
* Reversible cause of cryptozoospermia (i.e presence of a varicocele, febrile illness, or recent toxin exposure) Partial genital tract obstruction (i.e post-vaso-vasostomy, post-vasoepididymostomy, and low volume cryptozoospermia with ejaculatory duct obstruction)

Minimum Eligible Age

18 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

No