Evaluation of Treatment With Coenzyme Q10 and L-Carnitine on Semen Parameters in Infertile Men With Idiopathic Oligoasthenoteratospermia

NCT ID: NCT06342856

Last Updated: 2024-04-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

EARLY_PHASE1

Total Enrollment

120 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-06-15

Study Completion Date

2024-07-01

Brief Summary

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Evaluation of treatment with Coenzyme Q10 and L-Carnitine on Semen Parameters in Infertile men with Idiopathic Oligoasthenoteratospermia

Detailed Description

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Evaluation of treatment with Coenzyme Q10 and L-Carnitine on Semen Parameters in Infertile men with Idiopathic Oligoasthenoteratospermia a placebo controlled clinical trial

Conditions

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Infertility Unexplained Oligospermia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Group 1

will receive a daily dose of 200 mg of CoQ10 for 3 months

Group Type ACTIVE_COMPARATOR

co enzyme Q10 , L- Carnitine

Intervention Type DRUG

Patient fulfilling inclusion criteria after obtaining consent will be randomized into four equal groups randomization will be computer based

Group 2

will receive L-carnitine 1 tablet per day orally for 3 months

Group Type ACTIVE_COMPARATOR

co enzyme Q10 , L- Carnitine

Intervention Type DRUG

Patient fulfilling inclusion criteria after obtaining consent will be randomized into four equal groups randomization will be computer based

Group 3

will receive combination of a daily dose of 200 mg of CoQ10 and 1 tablet of L-carnitine for 3 months

Group Type ACTIVE_COMPARATOR

co enzyme Q10 , L- Carnitine

Intervention Type DRUG

Patient fulfilling inclusion criteria after obtaining consent will be randomized into four equal groups randomization will be computer based

Group 4

will receive a placebo for 3 months

Group Type PLACEBO_COMPARATOR

co enzyme Q10 , L- Carnitine

Intervention Type DRUG

Patient fulfilling inclusion criteria after obtaining consent will be randomized into four equal groups randomization will be computer based

Interventions

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co enzyme Q10 , L- Carnitine

Patient fulfilling inclusion criteria after obtaining consent will be randomized into four equal groups randomization will be computer based

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* of in¬fertility of 1 year or more without the use of contraception

Exclusion Criteria

* o Active genital infections.

* Patients with ejaculatory dysfunction
* Azoospermia
Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

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Ain Shams University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Ain Shams University

Cairo, , Egypt

Site Status RECRUITING

Countries

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Egypt

Central Contacts

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waleed,mo abdelhamid, ass lecturer

Role: CONTACT

01013340534 ext. wa

Facility Contacts

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ahmed ma maher, lecturer

Role: primary

01013340534

References

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Salvio G, Cutini M, Ciarloni A, Giovannini L, Perrone M, Balercia G. Coenzyme Q10 and Male Infertility: A Systematic Review. Antioxidants (Basel). 2021 May 30;10(6):874. doi: 10.3390/antiox10060874.

Reference Type RESULT
PMID: 34070761 (View on PubMed)

Other Identifiers

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idiopathic infertility

Identifier Type: -

Identifier Source: org_study_id

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