High Intensity Resistance Training and Possible Sarcopenia

NCT ID: NCT05985616

Last Updated: 2024-03-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

32 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-08-15

Study Completion Date

2024-01-19

Brief Summary

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Studies conducted so far added the dietary supplements along with resistance training as an intervention, we could not determine whether the observed effects of the intervention were due to the training program and/or dietary supplements.

Detailed Description

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This study will investigate the effects of high intensity resistance training solely in the possible sarcopenia cases which has not done before, to author's knowledge. Furthermore this study will help clinicians to individualize and optimize the therapy for specific patient subgroups, improve the potential of this therapy to improve human function and well being, facilitate timely interventions in community healthcare and prevention settings, which will contribute to higher awareness of sarcopenia prevention and interventions in diverse health care settings.

Conditions

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Sarcopenia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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Group A

High intensity (80-85% of 1RM) will be administered at alternative days for 16 weeks.

The exercise will have three phases; Phase I consists of 2-3 sets of 8-15 repetitions, Phase II will follow the single set approach and Phase III will have the Superset approach.

The following activities will be incorporated via resistance training: latissimus front pulleys, rowing, back extension, inverse fly, bench press, shoulder press, lateral raises, butterfly with extended arms, crunches, leg presses, leg extension and curls, leg adduction, abduction.

Group Type EXPERIMENTAL

High Intensity Resistance Training

Intervention Type OTHER

High intensity resistance training will be performed 3 times a day for sixteen weeks

Group B

No intervention will be provided in this group. The participants in this group will follow their usual daily activities.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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High Intensity Resistance Training

High intensity resistance training will be performed 3 times a day for sixteen weeks

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Both male and female
* Age more than 60 years
* Possible sarcopenia cases as defined by Asian Working Group for Sarcopenia (Handgrip strength: Male less than 26kg and Female less than 18kg, 5 time chair stand test more than/equals to 12 seconds)

Exclusion Criteria

* Orthopedic surgery in last one year
* Neurological disorders like stroke etc
* History of recent fractures
* Metabolic disorders like DM etc
* Actively involved in exercise programs
* Cognitive impairment that could confound the assessment
* Wheelchair or bed bound individuals
Minimum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Riphah International University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Mirza Obaid Baig, MSPT

Role: PRINCIPAL_INVESTIGATOR

Riphah International University

Locations

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Abbas Institute of Medical Sciences

Muzaffarabad, Azad Kashmir, Pakistan

Site Status

Countries

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Pakistan

References

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Kemmler W, Kohl M, Frohlich M, Jakob F, Engelke K, von Stengel S, Schoene D. Effects of High-Intensity Resistance Training on Osteopenia and Sarcopenia Parameters in Older Men with Osteosarcopenia-One-Year Results of the Randomized Controlled Franconian Osteopenia and Sarcopenia Trial (FrOST). J Bone Miner Res. 2020 Sep;35(9):1634-1644. doi: 10.1002/jbmr.4027. Epub 2020 Apr 28.

Reference Type BACKGROUND
PMID: 32270891 (View on PubMed)

Singh M, Stewart R, White H. Importance of frailty in patients with cardiovascular disease. Eur Heart J. 2014 Jul;35(26):1726-31. doi: 10.1093/eurheartj/ehu197. Epub 2014 May 26.

Reference Type BACKGROUND
PMID: 24864078 (View on PubMed)

Abdul-Hameed U, Rangra P, Shareef MY, Hussain ME. Reliability of 1-repetition maximum estimation for upper and lower body muscular strength measurement in untrained middle aged type 2 diabetic patients. Asian J Sports Med. 2012 Dec;3(4):267-73. doi: 10.5812/asjsm.34549.

Reference Type BACKGROUND
PMID: 23342225 (View on PubMed)

Other Identifiers

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REC01549 Shanza Nisar

Identifier Type: -

Identifier Source: org_study_id

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