Clinical Comparison of Application of Curcumin Gel in Pain Management After Free Gingival Graft Harvesting

NCT ID: NCT05819632

Last Updated: 2023-04-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-11-01

Study Completion Date

2024-04-01

Brief Summary

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The aim of this study is to compare the effect of using 2% curcumin gel versus gelatin sponge when applied to palatal donor site in pain management and wound healing after free gingival graft harvesting.

Detailed Description

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Conditions

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Palate; Wound

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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curcumin gel

the denuded palatal area will be superficially covered with a continuous thin layer of curcumin gel 2% one time immediately after the surgery (curcumin gel will be prepared in 2% concentration on a carbapol base)according to (Bhatia et al., 2014)

Group Type EXPERIMENTAL

curcumin gel 2%

Intervention Type OTHER

curcumin gel 2%

gelatine sponge

absorbable gelatin sponge will be cut to the palatal wound size and applied. Following manual compression of the wound area, both agents will be secured in place using compressive palatal sling sutures.

commercial name (CUTANPLAST)

Group Type ACTIVE_COMPARATOR

curcumin gel 2%

Intervention Type OTHER

curcumin gel 2%

Interventions

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curcumin gel 2%

curcumin gel 2%

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

1. Systematically healthy patient (American Society of Anesthesiology class I and II).
2. Male or female
3. Patients with mucogingival defects scheduled for free gingival graft.
4. Patients with good oral hygiene.

Exclusion Criteria

1. Patients with any uncontrolled local or systemic disease where periodontal plastic surgery might be contraindicated.
2. History of recent periodontal surgery at the donor site.
3. Smokers.
4. Pregnancy and lactation.
5. Patients allergic to the used agents,
6. Severe gagging reflex.
7. Inability or unwillingness to provide informed consent.
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Cairo University

OTHER

Sponsor Role lead

Responsible Party

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Tansim Khaled Tawfik Abdelrahman

masters degree candidate

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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tansim k abdelrahman, BDS

Role: PRINCIPAL_INVESTIGATOR

master student

mohamed Atef, PHD

Role: STUDY_DIRECTOR

Lecture of oral medicine and periodontology, faculty of dentistry ,Cairo university

manal m hosny, phd

Role: STUDY_CHAIR

Professor of oral medicine and periodontology factuality of Dentistry,Cairo university

Locations

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Faculty of Dentistry

Cairo, Manial, Egypt

Site Status RECRUITING

Countries

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Egypt

Central Contacts

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Tansim k ABdelrahman, BDS

Role: CONTACT

+201001086940

mohamed atef, PHD

Role: CONTACT

+201224302609

Facility Contacts

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mohamed atef, phd

Role: primary

+201224302609

Other Identifiers

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CairoU28122022

Identifier Type: -

Identifier Source: org_study_id

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