Soft Tissue Profile Following Socket Preservation With Platelet Rich Fibrin Versus Free Gingival Graft

NCT ID: NCT03628170

Last Updated: 2018-08-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

26 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-06-07

Study Completion Date

2019-02-28

Brief Summary

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Comparing socket preservation with Platelet -Rich Fibrin versus Free gingival graft.

Detailed Description

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Extraction of the non restorable tooth, then socket preservation is applied in experimental group using platelet rich fibrin, while in comparative group free gingival graft is applied with socket preservation.

Conditions

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Soft Tissue Mass

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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PRF (Platelet -rich fibrin) group

Extraction of the tooth followed by Platelet rich fibrin placed in the socket covered bu platelet rich fibrin membrane for socket preservation.

Group Type EXPERIMENTAL

platelet rich fibrin

Intervention Type OTHER

platelet rich fibrin will be prepared from patient's venous blood and inserted in the centrifuge at 2000 r.p.m. for 12 minutes Then, the Platelet rich fibrin plug will be placed in the socket after extraction for socket preservation covered by platelet rich fibrin membrane.

Free gingival graft group

Extraction of the tooth followed by using free gingival graft to cover the socket for socket preservation.

Group Type ACTIVE_COMPARATOR

Free gingival graft

Intervention Type OTHER

Free gingival graft will be taken from the palate to cover the socket after extraction of the tooth for socket preservation.

Interventions

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platelet rich fibrin

platelet rich fibrin will be prepared from patient's venous blood and inserted in the centrifuge at 2000 r.p.m. for 12 minutes Then, the Platelet rich fibrin plug will be placed in the socket after extraction for socket preservation covered by platelet rich fibrin membrane.

Intervention Type OTHER

Free gingival graft

Free gingival graft will be taken from the palate to cover the socket after extraction of the tooth for socket preservation.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Age range 25-50 years.
* Non- restorable teeth indicated for extraction.
* Good oral hygiene.
* Intact facial and lingual plates of bone, without infection or pathosis.
* Adequate apiacl bone for primaru stability

Exclusion Criteria

* Presence of uncontrolled Systemic disease eg: diabetes, bone disease or the use of medicines that interfere with bone metabolism, history of head and neck radiotherapy.
* Presence of periodontal and/or periapical infection.
* Smokers.
* Non-compliant patients.
* Pregnancy or lactation in females.
* History of head and neck radiotherapy.
Minimum Eligible Age

20 Years

Maximum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Cairo University

OTHER

Sponsor Role lead

Responsible Party

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Haya Hesham

Principle investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Faculty of Oral and dental medicine, Cairo University

Cairo, , Egypt

Site Status RECRUITING

Countries

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Egypt

Central Contacts

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Haya Hesham, Masters

Role: CONTACT

01272789994

Shaimaa Nasr, PhD

Role: CONTACT

01272789994

Facility Contacts

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Shaimaa Nasr, PhD

Role: primary

01272789994

Haya Hesham, Masters

Role: backup

01001421350

Other Identifiers

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version 3

Identifier Type: -

Identifier Source: org_study_id

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