Effects of Topical Hyaluronic Acid Gel on Postoperative Pain and Wound Healing
NCT ID: NCT05821725
Last Updated: 2025-11-25
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
30 participants
INTERVENTIONAL
2023-07-15
2023-11-21
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
SUPPORTIVE_CARE
DOUBLE
Study Groups
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Group I
A gel containing Hyaluronic acid in combination with a hemostatic sponge
Hyaluronic acid
Hyaluronic acid and hemostatic sponge
Group II
A hemostatic sponge alone
Control
Hemostatic sponge
Interventions
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Hyaluronic acid
Hyaluronic acid and hemostatic sponge
Control
Hemostatic sponge
Eligibility Criteria
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Inclusion Criteria
* Informed Consent Form signed and availability for the duration of the study
* Good general health (absence of any condition that, in the opinion of the Principal Investigator, might constitute a risk to the subject while participating in the study
* Clinical indication for mucogingival surgery that requires a de-epithelialized gingival graft (DGG) from the palate
* Willingness to provide information related to their medical history
* Minimum of 10 uncrowned permanent natural teeth (excluding third molars)
* Normal salivary flow
Exclusion Criteria
* Subject using anticonvulsants, antihistamines, antidepressants, sedatives, tranquilizers, anti-inflammatory medication or daily analgesics within one month prior to the start of the study or scheduled to start such intake during the course of the study
* Subject participating in any other clinical study
* Subject pregnant or breastfeeding
* Subject allergic to oral care products, personal care consumer products, or their ingredients
* Extended use of antibiotics or therapeutic mouthwash any time during the three months prior to entry into the study
* A medical history reporting that the subject has a current systemic or autoimmune disease, such as diabetes, lupus, etc
* Ongoing use of medications known to affect the gingival tissues (i.e. calcium channel blockers, phenytoin, cyclosporine)
18 Years
70 Years
ALL
Yes
Sponsors
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Colgate Palmolive
INDUSTRY
Responsible Party
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Principal Investigators
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Marcelo Faveri, DDS, PhD
Role: STUDY_DIRECTOR
Faveri Academy
Locations
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Faveri Academy
Guarulhos, São Paulo, Brazil
Countries
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Other Identifiers
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CRO-2022-09-WH-BZ-ZM
Identifier Type: -
Identifier Source: org_study_id
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