The Effect of Hyaluronic Acid Gel on Relieving Post-Implantation Pain

NCT ID: NCT05776290

Last Updated: 2023-04-07

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 11 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2021-02-15
• Study Completion Date: 2022-05-15

Brief Summary

Few previous studies have employed HA in the implant socket; instead, the majority have applied it topically to the area around dental implants after they have been placed. The application was done after suturing in these investigations. Therefore, the goal of the current study was to inject HA into the implant socket and onto the alveolar bone prior to implant insertion and suturing in order to preserve the HA for an extended period of time.

This study aims to use a visual analog scale (VAS) on the first, third, and tenth days following the surgical intervention to assess the efficacy of employing HA in dental implants in terms of pain reduction that may accompany dental implant surgery.

Conditions

Implant Complication

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: SINGLE

Study Groups

Hyaluronic acid injection

The hyaluronic acid will be injected into the implant socket before implantation.

Group Type: EXPERIMENTAL

Hyaluronic Acid

Intervention Type: BIOLOGICAL

This material will be injected into the prepared impact socket prior to inserting the implant. This injection will be done inside the socket as well as on the periphery of the socket.

Traditional treatment

The socket will be prepared in the normal manner without being injected with any material.

Group Type: NO_INTERVENTION

No interventions assigned to this group

Interventions

Hyaluronic Acid

This material will be injected into the prepared impact socket prior to inserting the implant. This injection will be done inside the socket as well as on the periphery of the socket.

Intervention Type: BIOLOGICAL

Eligibility Criteria

Inclusion Criteria

• bilateral tooth loss with a sufficient amount of bone volume
• no general problems
• good oral health
• age between 20 and 60 years

Exclusion Criteria

• the use of immunosuppressive drugs and corticosteroids for long periods
• the existence of serious systemic disorders
• contraindications for local anesthesia or oral surgery
• pregnant women and nursing mothers
• patients receiving chemotherapy or radiation
• alcoholics and heavy smokers.

• Minimum Eligible Age: 20 Years
• Maximum Eligible Age: 60 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Damascus University

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Waseem Al-Khateeb, DDS MSc

Role: PRINCIPAL_INVESTIGATOR

PhD student at the Department of Oral Medicine

Locations

Department of Oral Medicine, Faculty of Dentistry, University of Damascus

Damascus, , Syria

Countries

Syria

Other Identifiers

UDDS-OralMed-01-2023

Identifier Type: -

Identifier Source: org_study_id