Effect of Topical Application of Hyaluronic Acid on Stability of Immediate Loading Dental Implant in Posterior Maxilla

NCT ID: NCT05403099

Last Updated: 2022-06-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-03-01

Study Completion Date

2020-03-01

Brief Summary

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Effect of Topical Application of Hyaluronic Acid on Stability of Immediate Loading Dental Implant in Posterior Maxilla

Detailed Description

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Patients were randomly divided into two groups:

Group I (Control group):

Ten implants were placed in posterior maxilla and immediately loaded.

Group II (Study group):

Ten implants were coated with HA before placement in posterior maxilla and immediately loaded.

Conditions

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Missing Teeth

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Twenty implants were inserted in patients seeking for replacement of missed single or multiple posterior maxillary teeth. Patients were divided randomly into two groups. In the control group, ten implants were placed and immediately loaded. While in the study group, ten implants were coated with hyaluronic acid (HA) immediately before placement and immediately loaded. All patients were clinically evaluated at implant placement time, one, three and six months after loading regarding implant stability. Peri-implant pocket depth and modified sulcus bleeding index were evaluated clinically at six months in all patients. Bone density was evaluated radiographically after three months. All clinical and radiographic data were subjected to statistical analysis.
Primary Study Purpose

OTHER

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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control

Each implant was placed into the prepared implant site.

Group Type ACTIVE_COMPARATOR

conventional implant placement

Intervention Type OTHER

immediate placement of dental implant without application of hyaluronic acid on implant surface

Hyaluronic acid

Each implant was placed after topical application of HA on its surface

Group Type EXPERIMENTAL

Hyaluronic acid

Intervention Type OTHER

immediate placement of dental implant after topical application of hyaluronic acid on implant surface

Interventions

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Hyaluronic acid

immediate placement of dental implant after topical application of hyaluronic acid on implant surface

Intervention Type OTHER

conventional implant placement

immediate placement of dental implant without application of hyaluronic acid on implant surface

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Highly motivated patients with good oral hygiene.
* Age 18 years or older.
* Adequate alveolar bone volume at the implant site, at least 6mm in width and 15 mm in height.
* Free from any parafunctional habits

Exclusion Criteria

* Patients suffering from any systemic or local disease that contraindicate implant placement or surgery.
* Pregnancy.
* Smokers.
Minimum Eligible Age

20 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Mansoura University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Merna Elhadidi

Al Mansurah, , Egypt

Site Status

Countries

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Egypt

Other Identifiers

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01010119

Identifier Type: -

Identifier Source: org_study_id

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