Clinical Comparison of Topical Application of Alvogyl Versus Hyaluronic-Acid Gel in Management of Pain And Palatal Wound Healing

NCT ID: NCT05334745

Last Updated: 2022-04-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE1

Total Enrollment

16 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-12-01

Study Completion Date

2023-01-01

Brief Summary

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The aim of the study is to evaluate the effect of application of Alvogyl versus hyaluronic acid in decreasing postoperative pain and promoting healing in the palatal wound following the free gingival graft procedure

Detailed Description

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Postoperative pain and bleeding are the most common complications after palatal graft harvesting, also postsurgical swelling have been reported. Although hemostatic agents, mechanical barriers, bioactive materials, antibacterial and antiseptic agents and herbal products have been found effective in preventing such complications, an ideal support could not be specified for this purpose. Further, undesired side effects such as delayed wound healing/foreign body reaction have been reported .

No gold standard has been identified, thus there is a need for further investigations aiming to reach the best possible treatment modality for pain relief and prevention of reported complications following harvesting of palatal graft .

Conditions

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Wound Healing

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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application of Alvogyl in the palatal wound with stent

Group Type EXPERIMENTAL

Alvogyl

Intervention Type OTHER

application of Alvogyl in the palatal wound with stent versus hyaluronic acid application

application of 0.2% Hyaluronic acid is placed in the palatal wound with stent .

Group Type OTHER

Alvogyl

Intervention Type OTHER

application of Alvogyl in the palatal wound with stent versus hyaluronic acid application

Interventions

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Alvogyl

application of Alvogyl in the palatal wound with stent versus hyaluronic acid application

Intervention Type OTHER

Other Intervention Names

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Hyaluronic acid

Eligibility Criteria

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Inclusion Criteria

* Patients with mucogingival defects scheduled for free gingival graft
* Age from 18 years up to 60
* Medically healthy patient

Exclusion Criteria

* Systemic diseases that may be a contraindication for any surgeries.
* Loss of maxillary premolars and molars.
* Pregnancy or lactation
* Smoking
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Cairo University

OTHER

Sponsor Role lead

Responsible Party

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mohy eldin mahmoud aboelazayem

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Egypt

Cairo, , Egypt

Site Status RECRUITING

Countries

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Egypt

Central Contacts

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mohy eldin aboelazayem, TA

Role: CONTACT

+201005007001

shaimaa Nasr, PHD

Role: CONTACT

+01272789994

Facility Contacts

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mohyeldin aboelazayem, TA

Role: primary

+201005007001

shaimaa nasr, PHD

Role: backup

+201272789994

Other Identifiers

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01005007001

Identifier Type: -

Identifier Source: org_study_id

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