Cyanoacrylate Tissue Adhesives Versus Silk Suture at the Palatal Donor Site of Sub Epithelial Connective Tissue Graft

NCT ID: NCT04780360

Last Updated: 2021-03-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-02-01

Study Completion Date

2021-12-01

Brief Summary

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Subepithelial connective tissue grafts (CTG) are considered the gold standard procedure with proven clinical success when it comes to gingival augmentation aims to to improve periodontal health, which can enhance the long-term prognosis of teeth by obtaining soft tissue coverage of exposed root surfaces and/or augmentation the dimensions of gingival tissue. The procedure require harvesting tissue from a the palate, which increases the complexity of the procedure and patient discomfort. Complications after harvesting a graft would be pain, inflammation, bleeding, flap necrosis and infection in the donor site.

Detailed Description

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Conditions

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The Effect of Local Aplication of Cayanoacrylate Tissue Adhesives on Improving the Healing

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

DOUBLE

Investigators Outcome Assessors

Study Groups

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Cayanoacrylate tissue adhesives

thin layers of high viscosity blend of n-butyl and 2-octyl cayanoacrylate tissue adhesive will be applied and rinsed with saline at least three times with interval of at least 30 seconds

Group Type EXPERIMENTAL

Cayanoacrylate tissue adhesives

Intervention Type PROCEDURE

Cyanoacrylates are a family of strong fast-acting adhesives with industrial, medical, and household uses. They are various esters of cyanoacrylic acid. The acryl groups in the resin rapidly polymerize in the presence of water to form long, strong chains

Silk suture material

interrupted knots

Group Type ACTIVE_COMPARATOR

Silk suture

Intervention Type PROCEDURE

Non Absorbalble suture materiel used to fixed the edges of the incision in place until healing

Interventions

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Cayanoacrylate tissue adhesives

Cyanoacrylates are a family of strong fast-acting adhesives with industrial, medical, and household uses. They are various esters of cyanoacrylic acid. The acryl groups in the resin rapidly polymerize in the presence of water to form long, strong chains

Intervention Type PROCEDURE

Silk suture

Non Absorbalble suture materiel used to fixed the edges of the incision in place until healing

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Patients with mucogingival defects scheduled for sub epithelial connective tissue graft
* Age at least 18 years.
* Not having any systemic disease that could compromise wound healing
* No periodontal surgery on the experimental sites.
* No smoking,
* No pregnancy or lactation

Exclusion Criteria

* Patients with coagulation disorders
* patients on corticosteroids, with uncontrolled diabetes, or with any systemic disease that precluded periodontal surgery
* patients with a history of contact dermatitis to formaldehyde
* Loss of maxillary premolars and molars
* Medications or antibiotics used in the previous 6 months
* Pregnancy or lactation
* Smoking
Minimum Eligible Age

18 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Cairo University

OTHER

Sponsor Role lead

Responsible Party

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Mohamed Saeed Mohamed Ibrahuim Abdullah

Researcher

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Faculty of Dentistry, Cairo Universty

Cairo, , Egypt

Site Status RECRUITING

Countries

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Egypt

Central Contacts

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Mohamed S Mohamed Ibrahium Abdullah, Invistegator

Role: CONTACT

01283626196 ext. 02

Facility Contacts

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Hassan Ahmed, Adminstrator

Role: primary

23634965 ext. 02

Other Identifiers

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567

Identifier Type: -

Identifier Source: org_study_id

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