The Association Between SIRI and POD in Older Patients

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

116 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-03-01

Study Completion Date

2019-10-31

Brief Summary

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Postoperative delirium (POD) remains one of most common complication in elderly patients receiving surgery, which is characterized by acute and fluctuating change in the level of cognition and consciousness. Previous studies have shown that surgery and anesthesia-induced acute peripheral inflammation and neuroinflammation may lead to delirium after surgery. Systemic Inflammation Response Index (SIRI) is a more easily accessible and comprehensive inflammation marker derived from monocyte, neutrophil, and lymphocyte count, which has been investigated to assess the prognosis of cancer and infectious diseases. However, the relationship between SIRI and POD has yet to be investigated.

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Detailed Description

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Conditions

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Postoperative Delirium Elderly Surgery

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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POD group

Patients were considered to surfer from postoperative delirium by a positive Confusion Assessment Method (CAM) questionnaire after surgery.

No interventions assigned to this group

No-POD group

Patients did not surfer from postoperative delirium by a positive CAM questionnaire after surgery.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Hospital stay of at least 3 days
* More than or equal to 65 years old
* Elementary education or above
* Able to communicate
* American Society of Anesthesiologists (ASA) physical status I-III
* Mini-mental State Examination (MMSE) scores ≥ 22 points