Nutritional Management of Post COVID-19 Cognitive Symptoms

NCT ID: NCT05705648

Last Updated: 2025-07-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-10-01

Study Completion Date

2027-03-01

Brief Summary

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The goal of this clinical trial is to learn about in brain "fog" complaints associated with long-COVID in people aged 22-50-years. The main questions it aims to answer are:

* the natural course of brain "fog" complaints
* the effect, if any of supplemental dietary oil on brain "fog" complaints Participants will be asked to undergo some brain testing (X-rays and questions. Treatments they'll be given will be one of two supplemental oils to consume daily.

Researchers will compare outcomes in the two different oil groups to see if it has any effect on brain "fog" complaints.

Detailed Description

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Randomized placebo-control clinical trial comparing two types of nutritional oil and evaluating the impact, if any, on subjective complaints of long-COVID cognitive changes.

Conditions

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Long COVID

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Randomised placebo-controlled clinical trial
Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors
Double-blind, placebo control

Study Groups

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Intervention

Medium chain triglyceride oil 15ml tid x 5 months

Group Type EXPERIMENTAL

medium chain triglyceride oil

Intervention Type DIETARY_SUPPLEMENT

Medium chain triglyceride oil

Placebo

Safflower oil 15mls tid x 5 months

Group Type PLACEBO_COMPARATOR

Safflower oil

Intervention Type DIETARY_SUPPLEMENT

Safflower oil

Interventions

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medium chain triglyceride oil

Medium chain triglyceride oil

Intervention Type DIETARY_SUPPLEMENT

Safflower oil

Safflower oil

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* confirmed COVID infection, at least 3 months previously, with ongoing cognitive complaints
* all other medical conditions stable, and on stable doses of medications (if required)

Exclusion Criteria

* COVID infection not confirmed by PCR or Rapid test
* unable to speak English
* pre-COVID cognitve complaints, and/or medical diagnoses affecting cognitive function
Minimum Eligible Age

22 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Alberta

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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University of Alberta

Edmonton, Alberta, Canada

Site Status RECRUITING

Countries

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Canada

Facility Contacts

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Angela Juby, MBChB

Role: primary

(780) 492-6233

Other Identifiers

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Pro00109795

Identifier Type: -

Identifier Source: org_study_id

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