Oral Processing and Appetite in Older Adults

NCT ID: NCT05671003

Last Updated: 2024-07-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

88 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-01-15

Study Completion Date

2023-09-15

Brief Summary

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The goal of this observational study is to learn about changes in oral processing and appetite in older adults aged 65+ years old. The main question it aims to answer is if oral processing affects gastric emptying in older adults (≥65 years old).

Detailed Description

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* To investigate if food intake and satiety differ between faster and slower eaters, within older adults (≥65 years old).
* To assess if chewing rate, salivary flow rate, oral processing and gastric emptying differ between older adults (≥65 years old) with smaller versus bigger appetites.

Conditions

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Older Adults Appetitive Behaviour Food Intake Oral Processing

Study Design

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Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Eligibility Criteria

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Inclusion Criteria

* 65 years old or over (no upper age limit);each group will contain an equal number of male and female participants;
* living sufficiently local to attend the two visits needed;
* able to understand and communicate in English language.

Exclusion Criteria

* Diagnosed dysphagia;
* (recent) oral surgery that significantly affects eating and/or swallowing;
* diagnosis of type 1 or type 2 diabetes;
* participant undergoing current treatment for cancer;
* participants with zero natural teeth;
* severe loss of appetite and not able to finish a meal (based on CNAQ) and/or people on special or therapeutic diets that restrict the consumption of a full meal and/or the meals provided;
* not able to provide informed consent as defined by the T-CogS test (participants with T-CogS \< 22 will be excluded);
* participants having a pacemaker;
* not able to accept the two meal dishes provided and/or relevant food/ingredient included in the meals allergies or intolerances or aversions;
* not able to feed themselves.
Minimum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Bern

OTHER

Sponsor Role collaborator

Wageningen University

OTHER

Sponsor Role collaborator

Queen's University, Belfast

OTHER

Sponsor Role collaborator

University of Reading

OTHER

Sponsor Role lead

Responsible Party

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Miriam Clegg

Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Miriam Clegg, BSc, PhD

Role: PRINCIPAL_INVESTIGATOR

[email protected]

Locations

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University of Reading

Reading, , United Kingdom

Site Status

Countries

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United Kingdom

References

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Tada A, Miura H. Systematic review of the association of mastication with food and nutrient intake in the independent elderly. Arch Gerontol Geriatr. 2014 Nov-Dec;59(3):497-505. doi: 10.1016/j.archger.2014.08.005. Epub 2014 Aug 17.

Reference Type BACKGROUND
PMID: 25179444 (View on PubMed)

Pina GMS, Mota Carvalho R, Silva BSF, Almeida FT. Prevalence of hyposalivation in older people: A systematic review and meta-analysis. Gerodontology. 2020 Dec;37(4):317-331. doi: 10.1111/ger.12497. Epub 2020 Sep 23.

Reference Type BACKGROUND
PMID: 32965067 (View on PubMed)

Morley JE, Silver AJ. Anorexia in the elderly. Neurobiol Aging. 1988 Jan-Feb;9(1):9-16. doi: 10.1016/s0197-4580(88)80004-6.

Reference Type BACKGROUND
PMID: 2898107 (View on PubMed)

Krop EM, Hetherington MM, Nekitsing C, Miquel S, Postelnicu L, Sarkar A. Influence of oral processing on appetite and food intake - A systematic review and meta-analysis. Appetite. 2018 Jun 1;125:253-269. doi: 10.1016/j.appet.2018.01.018. Epub 2018 Feb 22.

Reference Type BACKGROUND
PMID: 29408331 (View on PubMed)

Other Identifiers

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UREC 22/29

Identifier Type: -

Identifier Source: org_study_id

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