Effect of Anesthesia Method on Neutrophil-Lymphocyte Ratio

NCT ID: NCT05628935

Last Updated: 2022-11-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

1 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-01-01

Study Completion Date

2021-11-01

Brief Summary

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The neutrophil/lymphocyte ratio (NLR) is a simple and inexpensive marker of the inflammatory response. NLR is affected not only by surgical trauma but also by the anesthetic method. The method of anesthesia can affect NLR, thereby modulating the inflammatory response and surgical outcomes. In this study, it was aimed to evaluate the relationship between blood NLR and anesthesia techniques in patients undergoing forearm surgery, and the secondary aim was to evaluate the relationship between Platelet/lymphocyte ratio (TLR), Mean Platelet Volume (MPV) and anesthesia techniques.

Detailed Description

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Conditions

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Inflammation Anesthesia

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Group G

Patients Undergoing Forearm Surgery under general anesthesia

No interventions assigned to this group

Group P

Patients Undergoing Forearm Surgery under peripheral nerve block

peripheral nerve block

Intervention Type PROCEDURE

local anesthetic application to the brachial plexus

Interventions

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peripheral nerve block

local anesthetic application to the brachial plexus

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Underwent forearm surgery
* Between aged 18-70
* Under general anesthesia or peripheral nerve block

Exclusion Criteria

* acute infection
* morbid obesity
* chronic treatment with steroids or immunosuppressants
* recently received chemotherapy
* hepatic and renal dysfunction;
* chronic alcohol abusers
* Multiple trauma
* Patients with missing data in their files
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Zonguldak Bulent Ecevit University

OTHER

Sponsor Role lead

Responsible Party

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Bengü Gülhan Köksal

medical doctor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Zonguldak Bülent Ecevit University Medicine Faculty

Zonguldak, Kozlu, Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

Other Identifiers

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2020-22/17

Identifier Type: -

Identifier Source: org_study_id

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