Postprandial Lipemia and Glycemia Following a High-Fat Meal

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

16 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-12-29

Study Completion Date

2022-06-01

Brief Summary

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The goal of this clinical trial is to determine the acute effects on postprandial lipemia and glycemia by supplementing a high-fat meal with either white button (WB) or shiitake (SH) mushroom powder in relatively healthy adults, aged 18 to 35.

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Detailed Description

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Conditions

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Hypercholesterolemia Postprandial Hyperglycemia Lipid Disorder

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Double-blind, randomized

Study Groups

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White Button Mushroom

368.5 grams of irradiated ground beef patty (80/20 lean mass to fat ratio) + 14 grams white button mushroom powder, and a Wegmans Food Market Brand Big Hawaiian bun

Group Type EXPERIMENTAL

Mushroom Powder

Intervention Type DIETARY_SUPPLEMENT

Ground shiitake mushrooms or ground white button mushrooms

Shiitake Mushroom

368.5 grams of irradiated ground beef patty (80/20 lean mass to fat ratio) + 14 grams Shiitake mushroom powder, and a Wegmans Food Market Brand Big Hawaiian bun

Group Type EXPERIMENTAL

Mushroom Powder

Intervention Type DIETARY_SUPPLEMENT

Ground shiitake mushrooms or ground white button mushrooms

Control

368.5 grams of irradiated ground beef patty (80/20 lean mass to fat ratio) and a Wegmans Food Market Brand Big Hawaiian bun.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Mushroom Powder

Ground shiitake mushrooms or ground white button mushrooms

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* generally healthy
* non-diabetic
* normal to mildly hypercholesterolemic (Total Cholesterol 200-239 mg/dL and LDL-C 130-159 mg/dL)
* have BMI \<30 or BF% (men \<25%, women \<32%)
* no known disease of the liver or gallbladder
* no documented problems with fat metabolism
* normal lipemic response to a lipid challenge
* No known mushroom allergy