The Validation and Development of Termination-of-Resuscitation (TOR) Rules in OHCA Patients in Asia Countries

NCT ID: NCT05545176

Last Updated: 2022-09-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

140000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2007-01-01

Study Completion Date

2032-12-31

Brief Summary

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Objectives/Hypotheses

1. Prehospital termination-of-resuscitation (TOR) rules were developed in North American and European sites. Whether they remained valid in different geographic, ethnic, and cultural background areas is still under debate.
2. Differences in characteristics of out-of-hospital cardiac arrests (OHCAs) and configurations of emergency medical service (EMS) between the Western and Asian countries, including relatively lower rate of presenting shockable rhythm (i.e. ventricular fibrillation / ventricular tachycardia; VF/VT), lower rates of bystander CPR, less advanced life support (ALS) implementation, and less public access defibrillators, might create potential threats to the prediction accuracy of TOR rules.
3. We aim to conduct a study to validate the performance of ever published TOR rules in Asian OHCA population, including non-traumatic, traumatic, and pediatric OHCA patients. Furthermore, assess the possible variables that may impact the performance of TOR rules.
4. We also aim to develop new TOR rules based on PAROS registry for Asia population, focusing on non-traumatic, traumatic, and pediatric OHCA patients, respectively.

Detailed Description

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Conditions

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Out-Of-Hospital Cardiac Arrest

Study Design

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Observational Model Type

OTHER

Study Time Perspective

OTHER

Study Groups

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out of hospital cardiac arrest patients in Asia countries

termination of resuscitation rules

Intervention Type OTHER

Use retrospective data to analyze the accuracy termination of resuscitation rules and further develope a termination of resuscitation rule.

Interventions

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termination of resuscitation rules

Use retrospective data to analyze the accuracy termination of resuscitation rules and further develope a termination of resuscitation rule.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* out of hospital cardiac arrest (OHCA) patients

Exclusion Criteria

* age \<18 years
* non-EMS transport to the emergency department
* obvious signs of death (e.g. decapitation, rigor mortis, lividity, and decapitation) or having do-not-resuscitate (DNR) orders
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Singapore Clinical Research Institute

OTHER

Sponsor Role collaborator

National Taiwan University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Shu-Hsien Hsu, MPH

Role: PRINCIPAL_INVESTIGATOR

National Taiwan University

Locations

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National Taiwan University

Taipei, , Taiwan

Site Status RECRUITING

Countries

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Taiwan

Central Contacts

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Shu-Hsien Hsu, MPH

Role: CONTACT

Facility Contacts

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Shu-Hsien Hsu, MPH

Role: primary

Other Identifiers

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202206030RINC

Identifier Type: -

Identifier Source: org_study_id

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