Automatic Ventilation in Prehospital Resuscitation on OHCA
NCT ID: NCT06067204
Last Updated: 2024-11-27
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
514 participants
INTERVENTIONAL
2023-10-02
2026-09-30
Brief Summary
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1. How does automatic ventilation affect OHCA patients' survival and prognosis comparing to manual ventilation.
2. What are the differences on resuscitation qualities between automatic ventilation and manual ventilation.
Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
TRIPLE
Study Groups
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Automatic ventilation
After the advanced airway is placed, an automatic pneumatic ventilator will be connected and provides ventilation in every 6 seconds.
Automatic ventilation
The FDA-approved device used is "Meditech" MICROVENT RESUSCITATOR, which is connected to the endotracheal tube, supraglottic airway or tracheostomy tube. It is powered by the airflow from the oxygen tank and provides ventilation in fixed interval. It has a pressure valve which will release the pressure once the airway pressure exceeds its threshold. In the current study, the threshold is set at 60 mmH2O. The tidal volume is set at 500-600 ml.
Manual ventilation
After the advanced airway is placed, a bag valve mask resuscitator will be connected and provides ventilation in every 6 seconds by the emergency medical technician.
Manual ventilation
The adult size bag-valve mask is connected to the endotracheal tube, supraglottic airway or tracheostomy tube. The interval, pressure and volume of the ventilation is controlled by the emergency medical technicians.
Interventions
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Automatic ventilation
The FDA-approved device used is "Meditech" MICROVENT RESUSCITATOR, which is connected to the endotracheal tube, supraglottic airway or tracheostomy tube. It is powered by the airflow from the oxygen tank and provides ventilation in fixed interval. It has a pressure valve which will release the pressure once the airway pressure exceeds its threshold. In the current study, the threshold is set at 60 mmH2O. The tidal volume is set at 500-600 ml.
Manual ventilation
The adult size bag-valve mask is connected to the endotracheal tube, supraglottic airway or tracheostomy tube. The interval, pressure and volume of the ventilation is controlled by the emergency medical technicians.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Attended by the Hsinchu County Fire Department for emergency medical assistance.
Exclusion Criteria
* OHCA caused by trauma.
* Return of spontaneous circulation (ROSC) observed at the scene.
* Clearly deceased at the scene (reaching conditions such as decomposition, rigor mortis, severe burns, decapitation, evisceration, or trunk fracture).
* Refusal of medical transportation by family members.
* No placement of an advanced airway throughout the procedure.
18 Years
ALL
No
Sponsors
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National Taiwan University Hospital
OTHER
Responsible Party
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Principal Investigators
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Edward Pei-Chuan Huang, M.D., M.S.
Role: STUDY_CHAIR
National Taiwan University Hospital
Locations
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National Taiwan University Hospital Hsinchu Branch
Hsinchu, , Taiwan
Countries
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Central Contacts
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Facility Contacts
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References
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Fan CY, Huang SS, Chen CH, Sung CW, Chang CH, Hung TH, Liu YC, Huang EP. Prehospital ventilation strategies in out-of-hospital cardiac arrest: A protocol for a randomized controlled trial (PIVOT trial). Resusc Plus. 2024 Nov 16;20:100827. doi: 10.1016/j.resplu.2024.100827. eCollection 2024 Dec.
Other Identifiers
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202304132RINB
Identifier Type: -
Identifier Source: org_study_id