Prognostic Indicators of Survival Following Cardiopulmonary Resuscitation in Patients With Cardiac Arrest

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Total Enrollment

120 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-01-01

Study Completion Date

2020-01-01

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Cardiopulmonary resuscitation (CPR) occurs approximately 200,000 times/yr in hospitals in the UnitedStates, with 18% of patients surviving to discharge. Just over half of these survivors are neurologically intact or with mild defiits at the time of discharge. Do-not-resuscitate (DNR) orders are used to withhold CPR from patients who are unlikely to benefi or for whom it is inconsistent with their treatment goals or personal preferences. It would be helpful to identify patients with a very low likelihood of survival to discharge neurologically intact or with mild defiits were they to experience cardiopulmonary arrest (CPA), so their physician can present the option of a DNR order. This information would also be useful anytime a patient raises the question of the likelihood of survival should they undergo CPA.The objective of this study was to determine key indicators for good outcome in patients with sudden cardiac arrest undergoing CPR and develop a prediction model to predict survival to hospital discharge in these patients.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Predictors for Survival and Good Neurological Outcome in E-CPR and Non CPR Treated Patients

NCT04198792

Cardiac Arrest Extracorporeal Membrane Oxygenation Hypoxia-Ischemia, Brain

RECRUITING

Identification of Ventricular Fibrillation and Optimization of Defibrillation During CPR

NCT02952105

Cardiac Arrest Identify of Electrocadiac Rhythm

UNKNOWN

Impact of NIRS-guided Cardiopulmonary Resuscitation After Cardiac Arrest on Resuscitation Rate

NCT03911908

Cardiac Arrest Cardiopulmonary Arrest With Successful Resuscitation Cerebral Oxygenation

UNKNOWN PHASE2

Continuous Chest Compressions vs AHA Standard CPR of 30:2

NCT01372748

Out of Hospital Cardiac Arrest

COMPLETED PHASE4

The Systematic Approach for Identification of Cause Among Out-of-hospital Cardiac Arrest Survivors

NCT06012838

Out-Of-Hospital Cardiac Arrest

COMPLETED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

A CPR coordinator prospectively collected data for the CPR registry according to the Utstein-style guidelines. Te registry included the following information:

demographic data, comorbidities, whether the arrest was witnessed, the incidence of suspected or confrmed trauma, presumed arrest time; presence of bystander CPR, frst documented arrest rhythm by the emergency medical service (EMS) provider, any return of spontaneous circulation (ROSC), presence of ECPR, the presence of return of spontaneous heart beating (ROSB) after CPR, presumed cause of arrest; the application of therapeutic hypothermia and the use of coronary angiography(CAG) or percutaneous coronary intervention (PCI),24-hour survival, the presence of ROSC more than 20 min, hospital length of stay (LOS), survival to hospital discharge,Glasgow-Pittsburgh cerebral performance category (CPC) score at discharge, and the fnal diagnosis at discharge. Te comorbidity score was calculated using the Charlson comorbidity index. Te duration of CPR was defned as the time interval from the frst chest compression provided by healthcare providers to the termination of resuscitation eforts due to ROSC (more than 20 min),ROSB after CPR, or a declaration of death. A favorable neurologic outcome was defned as a CPC score of 1 or 2 on the fve-category scale.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Cardiopulmonary Resuscitation

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Cardiopulmonary resuscitation

Cardiopulmonary resuscitation (CPR) is an emergency treatment for patients with respiratory arrest and cardiac arrest in an attempt to restore the patient to spontaneous breathing and heartbeat through cardiopulmonary resuscitation

Intervention Type PROCEDURE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* age more than 18 years,
* sudden arrest with potentially reversible causes,
* a short no fow time (time interval from presumed arrest to CPR initiation)
* even for unwitnessed arrests

Exclusion Criteria

* presence of a terminal illness or malignancy, severe irreversible neurologic defcit,
* suspected or confrmed traumatic origin of arrest,
* no informed consent from the family

Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No