The Influence of Daily Honey Consumption on IR in Obese Women With IR
NCT ID: NCT05427799
Last Updated: 2026-01-27
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
20 participants
INTERVENTIONAL
2022-03-01
2024-11-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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Honey
Treatment with honey will extend for four months and the actual treatment phases will be preceded by a 2-week run-in period, in which the participants will be asked to refrain from honey consumption.
During the six months intervention, a daily dose of 0.5 g/kg body weight of honey will be consumed by each participant. Participants will be provided with Mixed flora honey that will be obtained from local producers. The daily dose of treatments will be divided into two doses to simulate a natural pattern of consumption.
All participants will be required to limit the consumption of caffeinated beverages to two beverages a day during the study periods.
A nutritionist will calculate the energy requirement and provide dietary instructions and a nutritionally adequate, hypocaloric, balanced sample diet plan with a fixed macronutrient composition of 28% fat, 55% carbohydrate, and 17% protein will be individualized for each participant monthly.
Honey
A mixed flora honey that will be obtained from local producers. and will be consumed by a daily dose of 0.5 g/kg body weight of honey by each participant and will be divided into two doses.
Other carbohydrate alternatives
Treatment with simple sugar alternatives (other carbohydrates, such as jell-o) will extend for four months and the actual treatment phases will be preceded by a 2-week run-in period, in which the participants will be asked to refrain from honey consumption, and during the study periods.
A daily dose of 0.5 g/kg body weight of jell-O will be consumed by each participant and will be divided into two doses to simulate a natural pattern of consumption. Jell-O was selected as a source of sucrose with negligible phenolic capacity, which will serve as a control.
All participants will be required to limit the consumption of caffeinated beverages to two beverages a day during the study periods.
A nutritionist will calculate the energy requirement and provide dietary instructions and a nutritionally adequate, hypocaloric, balanced sample diet plan with a fixed macronutrient composition of 28% fat, 55% carbohydrate, and 17% protein will be individualized for each participant monthly.
Other carbohydrate alternatives such as jell-o
A daily dose of 0.5 g/kg body weight of Jell-O will be consumed by each participant and will be divided into two doses. Jell-O was selected as a source of sucrose with negligible phenolic capacity.
Interventions
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Honey
A mixed flora honey that will be obtained from local producers. and will be consumed by a daily dose of 0.5 g/kg body weight of honey by each participant and will be divided into two doses.
Other carbohydrate alternatives such as jell-o
A daily dose of 0.5 g/kg body weight of Jell-O will be consumed by each participant and will be divided into two doses. Jell-O was selected as a source of sucrose with negligible phenolic capacity.
Eligibility Criteria
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Inclusion Criteria
* 19-45 years
* Obese (BMI \>= 30 kg/m\^2)
* Premenopausal
Exclusion Criteria
* Individual who previous insulin treatment
* Smokers
* Individual who have diabetes, kidney, liver, or hormonal diseases
* Individual who have significant weight changes \> 5% during the past 6 months
* Women who are postmenopausal
19 Years
45 Years
FEMALE
No
Sponsors
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Abdul Hameed Shoman Foundation
UNKNOWN
University of Jordan
OTHER
Responsible Party
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Shatha Hammad, Assistant Professor
Assistant Professor
Principal Investigators
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Shatha S Hammad, PhD
Role: PRINCIPAL_INVESTIGATOR
The University of Jordan
Locations
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Jordan University Hospital
Amman, Amman, Jordan, Jordan
The University of Jordan
Amman, Amman, Jordan, Jordan
Countries
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References
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Abu Rajab, A., Takruri, H., Mishal, A., & Alkurd, R. Glycemic and Insulinemic Response of Different Types of Jordanian Honey in Healthy and Type 2 Diabetic Volunteers. Pakistan Journal of Nutrition, 2017; 16(2), 61-68.
Ajibola A., Physico-Chemical and Physiological Values of Honey and Its Importance as a Functional Food, International Journal of Food Sciences and Nutrition, 2015;2(6):1-9.
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Bermudez V, Salazar J, Martinez MS, Chavez-Castillo M, Olivar LC, Calvo MJ, Palmar J, Bautista J, Ramos E, Cabrera M, Pachano F, Rojas J. Prevalence and Associated Factors of Insulin Resistance in Adults from Maracaibo City, Venezuela. Adv Prev Med. 2016;2016:9405105. doi: 10.1155/2016/9405105. Epub 2016 Aug 4.
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Tartibian B, Maleki BH. The effects of honey supplementation on seminal plasma cytokines, oxidative stress biomarkers, and antioxidants during 8 weeks of intensive cycling training. J Androl. 2012 May-Jun;33(3):449-61. doi: 10.2164/jandrol.110.012815. Epub 2011 Jun 2.
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Related Links
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Type 2 diabetes as an inflammatory disorder
Prevalence and Associated Factors of Insulin Resistance in Adults from Maracaibo City, Venezuela
Other Identifiers
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2021/137
Identifier Type: -
Identifier Source: org_study_id
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