Glycemic Control Following Occupational Work in a Hot Environment

NCT ID: NCT06982612

Last Updated: 2025-05-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-05-31

Study Completion Date

2026-10-01

Brief Summary

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Occupational workers regularly perform physically demanding tasks in hot environments, exposing them to heat stress and potential dehydration. While the physiological impacts of heat exposure are well-documented, its effects on glycemic control remain less understood. Given the rising global temperatures due to climate change and the increasing prevalence of metabolic disorders such as obesity and type 2 diabetes, it is essential to investigate how heat exposure during work influences glycemic regulation. Understanding these interactions will help inform future occupational health guidelines and metabolic health recommendations in physically demanding industries.

Detailed Description

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Conditions

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Plasma Glucose Following Prolonged Heat Exposure

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Randomised, crossover design
Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Hot condition

Light exercise in a hot environment with ad libitum water intake

Group Type EXPERIMENTAL

Hot environment

Intervention Type OTHER

Participants exercising in a 36 degrees celsius environment

Temperate condition

Light exercise in a temperate environment with ad libitum water intake

Group Type EXPERIMENTAL

Temperate condition

Intervention Type OTHER

Participants exercising in a 18 degrees celsius environment

Interventions

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Hot environment

Participants exercising in a 36 degrees celsius environment

Intervention Type OTHER

Temperate condition

Participants exercising in a 18 degrees celsius environment

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Male or female
* Generally fit and healthy
* Participate in endurance or intermittent exercise at least 3 times a week or minimum of 150 minutes moderate intensity activity per week

Exclusion Criteria

* Under 18 or 45 and over,
* any morbidity or medication that might influence carbohydrate/fat metabolism (i.e., liver/renal/cardiovascular disease) or cycling ability (musculoskeletal injury etc),
* coagulation or bleeding disorders,
* blood-borne illness,
* heart conditions,
* congenital heart disease,
* uncontrolled exercise-induced asthma,
* smoking (including vaping),
* allergies to the products used in the study,
* dieting or restrained eating behaviours.
Minimum Eligible Age

18 Years

Maximum Eligible Age

45 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Loughborough University

OTHER

Sponsor Role lead

Responsible Party

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Stephen Mears

Dr - Senior lecturer

Responsibility Role PRINCIPAL_INVESTIGATOR

Central Contacts

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Stephen A Mears, PhD

Role: CONTACT

+44 1509 226391

Other Identifiers

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LEON21544

Identifier Type: -

Identifier Source: org_study_id

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