Evaluation of Cognitive and Motor Neurological Disorders in the Short and Long Term After Surgery for the Removal of a Diffuse Low-grade Glioma of the Supplementary Motor Area

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

22 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-05-19

Study Completion Date

2022-06-23

Brief Summary

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Background : The supplementary motor area is the most common/preferential brain location of LGG. This area plays an important role in many motor and cognitive functions such as motor initiation, bimanual coordination and executive functions. Many studies describe the supplementary motor area syndrome resulting from lesions in this area. News managements for LGGs consisting in intraoperative mapping in awake patients reduce significantly neurological disorders and increase also the overall survival . However, the literature does not provide data concerning motor and cognitive functions in a long term and their consequences in the quality of life of patients.

Objective : The aim of our research project is to identify whether there are some motor or neurocognitive deficit in the short and the long term in a population of patients who have medical story of LGG resection in the supplementary motor area.

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Detailed Description

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Patients and Methods : 20 patients who have medical story of LGG in the supplementary motor area and 20 patients who have medical story of LGG resection in other locations are recruited. Firstly, patients have to complete a self-assessment questionnaire about their quality of life, sent by regular mail or e-mail. Then, patients are admitted on the same day as their follow up visit and underwent motor and neurocognitive screening tests ( "Bilan des 400 points", Tests of Attentional Performances) for an hour. The investigators will analyse data and compare between the 2 groups.

Conditions

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Cognitive Disorders Motor Disorders Low-grade Glioma

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Case

patients with a history of surgical removal of diffuse low grade glioma located in the supplementary motor area

Test battery

Intervention Type OTHER

motor and neuropsychological test battery

Control

patients with a history of surgical removal of diffuse low-grade glioma located in another brain area

Test battery

Intervention Type OTHER

motor and neuropsychological test battery

Interventions

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Test battery

motor and neuropsychological test battery

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* 18 years of age or older
* Have a history of low-grade diffuse glioma resection
* Visiting the University Hospital for a follow-up neurosurgical consultation
* Underwent awake surgery

Exclusion Criteria

* Presence of cognitive disorders that do not allow the proposed test battery to be performed
* Under guardianship or curatorship
* Opposition to the participation to the research

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No