The Effect of Exercise and Metformin on Carotid Intima-media Thickness in Patients With Prediabetes
NCT ID: NCT05052918
Last Updated: 2022-06-22
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
90 participants
INTERVENTIONAL
2021-09-08
2023-03-15
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NON_RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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Exercise
Patients with prediabetes undergoing a 12-week exercise program
(1 hour of moderate-intensity aerobic exercise 3 days a week for 12 weeks)
Exercise
1 hour of moderate-intensity aerobic exercise 3 days a week for 12 weeks
Control
Patients with prediabetes with no intervention
No interventions assigned to this group
Metformin
Patients with prediabetes using metformin
No interventions assigned to this group
Interventions
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Exercise
1 hour of moderate-intensity aerobic exercise 3 days a week for 12 weeks
Eligibility Criteria
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Inclusion Criteria
* Those who have sufficient motivation to participate in the exercise program (will be evaluated by a one-on-one interview by the researchers)
* Have the same weight for 6 months before participating in the study (±2.5 kg)
* Those diagnosed with prediabetes by oral glucose tolerance test and/or HbA1c measurement
Exclusion Criteria
* Having cardiovascular disease
* Being diabetic
* Using metformin before participating in the study
* Receiving hormone replacement therapy
* Life expectancy less than 1 year
* HIV positivity
* Substance use
* Functional dependency
* Cognitive weakness
* Those who have other diseases that will affect the results of the study (respiratory diseases, muscle diseases, etc.)
* Those who use drugs or supplements that will affect the results of the study
18 Years
60 Years
ALL
No
Sponsors
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Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
OTHER
Responsible Party
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Principal Investigators
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Elif Yıldırım Ayaz, M.D.
Role: PRINCIPAL_INVESTIGATOR
Sultan Abdülhamid Han Training and Research Hospital
Locations
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Sultan Abdülhamid Han Training and Research Hospital
Üsküdar, Istanbul, Turkey (Türkiye)
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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EXERCISECIMT
Identifier Type: -
Identifier Source: org_study_id
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