Exercise as Cardio Protective Modulates in Diabetic Patients

NCT ID: NCT03925519

Last Updated: 2019-04-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

50 participants

Study Classification

OBSERVATIONAL

Study Start Date

2013-01-25

Study Completion Date

2014-05-26

Brief Summary

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* Physical exercise for 6 months produced significant improvement in adiponectin, hs-CRP, and nitric oxide (NO) and was significantly correlated with adiposity markers, lipid profile and glycemic control factors in both obese and non-obese diabetic patients.
* Patients with good physical activity reported a significant decrease in BMI, CHD risk scores, reduced hs-CRP, an increase in the levels of adiponectin and nitric oxide.
* In patients with type 2 diabetes mellitus, adiposity markers, lipid profile, hs-CRP, and adiponectin were significantly improved following moderate exercise interventions

Detailed Description

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To elucidate the potential role of exercise as anti-adiposity and anti-cardio protective modulates, we thought to investigate the effect of supervised aerobic training of moderate intensity on adiposity markers, nitric oxide level, plasma adiponectin, hs-CRP, and its association with CHD risk score in obese and non-obese patients with type 2 diabetes.

Conditions

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Diabetes Mellitus Exercise

Study Design

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Observational Model Type

OTHER

Study Time Perspective

RETROSPECTIVE

Study Groups

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non-obese

non-obese diabetic patients (n= 25, BMI ≤ 30 kg/m2) were subjected to supervised aerobic exercise

No interventions assigned to this group

obese group

obese diabetic group (n= 25, BMI ≥ 30 kg/m2)

Supervised aerobic exercise

Intervention Type OTHER

Interventions

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Supervised aerobic exercise

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* patients with type 2 diabetes for more than 5 years.
* Patients who were diagnosed according to the criteria of the American diabetes association.
* Not receiving any drugs affecting the data obtained
* had Normal daily diets
* Not participating in any other exercise programs
* Without any musculoskeletal disorders affecting an exercise program
Minimum Eligible Age

45 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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King Saud University

OTHER

Sponsor Role lead

Responsible Party

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Sami Gabr

clinical Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Other Identifiers

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RRC-2013-010

Identifier Type: -

Identifier Source: org_study_id

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